Astana Open Odds & First Round Predictions

• The Astana Open begins on Monday, October 3rd, with numerous intriguing names in the draw
• Carlos Alcaraz, Daniil Medvedev, Novak Djokovic, and Stefanos Tsitsipas are among the Astana Open betting favorites
• Read on for the Astana Open first-round odds and picks

Monday marks the beginning of another ATP 500 tournament as the tour heads to Kazakhstan for the Astana Open. World No. 1 Carlos Alcaraz will be looking for his sixth title of 2022 after his dramatic win at the US Open last month. In total, six of the top-10 players in the world are in the draw, with the likes of Daniil Medvedev, Stefanos Tsitsipas, Felix Auger-Aliassime, and even Novak Djokovic, who earned a wild-card berth. Keep reading for the Astana Open predictions and odds.

Astana Open Winner Odds

Odds as of October 2nd at Barstool Sportsbook. Claim an ESPN BET promo code.

By no surprise, Alcaraz is the co-tournament favorite at +250 alongside Djokovic. Medvedev is the third-favorite at +525 as he aims to turn around a subpar season, while Tsitsipas is fourth at +700. Nole looked fantastic in Tel Aviv, rolling to the finals without dropping a set. He’ll square off with Marin Cilic in the finale at 11:30 am ET today.

Pick to win: Novak Djokovic +250

Astana Open First-Round Odds

Odds as of October 2nd at Barstool Sportsbook. *Sinner suffered an injury in Sofia and could be out for Astana.

Four players, including No. 5 seed Andrey Rublev, await their first-round opponents after the conclusion of the qualifying rounds.

Maxime Cressy vs Karen Khachanov Prediction

This will be the first-ever meeting between No. 34 Maxime Cressy and No. 18 Karen Khachanov. Cressy has a 23-21 record in 2022 and ultimately retired in the first round of the US Open against Hungarian Marton Fucsovics due to injury. He did earn an impressive straight-sets victory over Sebastian Korda in Tel Aviv on September 28th but lost in the quarterfinals to Constant Lestienne on Thursday.

Karen Khachanov takes down Nick Kyrgios to advance to the US Open Semifinal 💪 pic.twitter.com/yuoU42UcO9

— Bleacher Report (@BleacherReport) September 7, 2022

Khachanov is coming off a very impressive run in Flushing Meadows, progressing all the way to the semifinals only to lose to Casper Ruud, who ended up falling in the final to Alcaraz. Khachanov beat some impressive players along the way though, including Pablo Carreno-Busta and fan favorite Nick Kyrgios in the quarterfinals in what was an absolute battle. The Russian’s big serve and relentless return play definitely were a factor in his fantastic showing in New York. This is his first tournament since the US Open.

Khachanov has the momentum and confidence right now. I’m liking him to win in straight sets here.

Pick: Karen Khachanov 2-0 (+155)

Cristian Garin vs Novak Djokovic Prediction

Cristian Garin and Novak Djokovic face off at the Astana Open. Both meetings have gone the way of the Serb, with their most recent clash coming at Wimbledon in 2021 in the Round of 16. Garin hasn’t played since the US Open, where he beat Jiri Lehecka in four sets in the opening round and then lost to Aussie Alex de Minaur in the second round.

"My main goal is to play the ATP Finals. I know I have to be in the top 20 and now I am 15th or 16th. I decided to play in Tel Aviv and Astana, then Paris and I hope Turin."

Novak Djokovic at the Masters, do you think he can make it? pic.twitter.com/HrZkncTvcY

— We Are Tennis (@WeAreTennis) September 26, 2022

Nole was of course axed from playing in New York because of his vaccination status, but that hasn’t stopped him from still playing top-tier tennis. He’s in the Tel Aviv final on Sunday against Croatian Marin Cilic as the legend searches for his 89th career title. Djokovic will have a quick turnaround for this Garin match but that shouldn’t be a big deal.

Both previous meetings were straight-set victories for Djokovic. But, Garin didn’t get totally swept off his feet. I’m liking a specific games bet.

Pick: Over 18.5 Games (-106)