Lazio vs Inter Milan Odds & Prediction – Serie A Round 3 (Aug 26)

By John Dillon in Soccer News
Published:

- Two undefeated teams meet at the Olympic Stadium in Rome at 2:45 pm ET on Friday
- Inter has won twice so far, while Lazio has won once and drawn once
- See all the odds and best bets for Lazio vs Inter Milan in Serie A Round 3
Two unbeaten Italian Serie A teams meet in Lazio vs Inter Milan on Friday.
Inter is in second place and level on points with leader Napoli after winning both of its opening games. They’re both among the favorites in the Serie A odds.
Lazio, meanwhile, is in the eighth spot after a win and a draw.
Lazio vs Inter Milan Odds
Result | Moneyline |
---|---|
Lazio | +310 |
Inter | -120 |
Draw | +255 |
Odds as of August 25 at DraftKings Sportsbook. Claim this DraftKings Sportsbook promo code before betting on the match.

In its opening game of the season, Lazio was a 2-1 winner at home against Bologna.
Following that, there was a 0-0 draw at Torino last weekend.

Meanwhile, Inter has begun its campaign against two of Serie A’s minor teams.
Firstly, there was a 2-1 win at Lecce. Then, subsequently, there was a 3-0 home defeat of Spezia.
There was a fifth-placed finish for Lazio last season and this term, it is looking to further embed coach Sarri’s highly-detailed and technical style.
Inter boss Simone Inzaghi says that Romelu Lukaku and Milan Skriniar ‘are improving’ and hopes Ciro Immobile ‘takes a break tomorrow.’ https://t.co/cwqfAPFXVp #FCIM #Inter #LazioInter #Calcio #SerieA #Inzaghi #Lazio
— Football Italia (@footballitalia) August 25, 2022
Furthermore, Inter – with its 5-3-2 formation – was runner-up in 2021 -22 to city rivals AC Milan.
It is hoping to regain the title it won in 2020-21 following the return of powerful striker Romelu Lukaku.
He was instrumental in that championship win and has now exited from an unhappy spell at Chelsea.
Lazio vs Inter Milan Prediction
At DraftKings Sportsbook, Inter is significantly favored for an away win at -120.
Meanwhile, Lazio is priced at +310. The draw is +255 – with kick-off at Rome’s Olympic Stadium at 2:45 pm ET.
Over/Under & Spread
Inter has scored five times in two relatively easy fixtures while Lazio has only two goals- and has already featured in a goalless stalemate.
However, it was the first time Lazio had failed to find the net in its last 10 most recent Serie A fixtures.
Even so, Lazio vs Inter Milan looks like it will be a tight contest.

That makes the offer of +120 for there to be fewer than three goals in Lazio vs Inter Milan the most compelling one (Under 2.5).
Backing the favorites, Inter, on the spread of -1.5 has odds of +225.
Romelu Lukaku to Score Odds
Belgian international Lukaku has already opened his Serie A account for this season – scoring after just two minutes in the opening win against Lecce.
He scored 64 times in 95 appearances in his previous two-season spell with Inter.
Manchester United target Sergej Milinkovic-Savic will soon hold talks over a new Lazio contract.
The Red Devils made what has been described as a “poor ” attempt to sign the Serbian earlier this summer. #MUFC #MUFC_FAMILY pic.twitter.com/pAiYXS0FfY— The Transfer Exchange Show (@TheTransferEx) August 25, 2022
Therefore, he is the favorite to be first on target in Lazio vs Inter Milan at +300.
Lazio skipper Ciro Immobile is just as prolific and hit 27 Serie A goals for the team last season.
Lazio vs Inter Milan Statistics
1 | Wins | 2 |
1 | Draws | 0 |
0 | Losses | 0 |
2 | Goals | 5 |
1 | Goals Against | 1 |
7 | Yellow Cards | 2 |
1 | Red Cards | 0 |
1 | Clean Sheets | 1 |
*Statistics from Serie A 2022-23.
He, too, has already found the net this season – getting the winner in the opening day defeat of Bologna.
Therefore, Immobile is priced at +400 to score first in Lazio vs Inter Milan.
Inter’s Lautaro Martinez is also priced at +400 after getting his first goal of the season in the second-game victory against Lecce.

Lazio’s Edin Dzeko is priced at +450 in this market.
There is value to be had in following Lazio’s Sergej Milinkovic-Savic who has scored five career goals against Inter and is priced attractively at +900.
Lazio vs Inter Milan Projected Line-Ups & Injuries
Here are the projected lineups and injuries for Friday’s match.
Lazio projected lineup: Provodel; Lazzarri, Romagnoli, Patric, Marusic; Vecino, Cataldi, Milinkovic-Savic; Pedro, Immobile, Zaccagni
Lazio Injuries: None
Inter Milan projected lineup: Handanovic; Skriniar, De Vrij, Bastoni; Dumfries, Calhanoglu, Brozovic, Barella, Dimarco; Martinez, Lukaku
Inter Milan Injuries: Dalbert, Mikhitaryan
There was a 3-1 win for Lazio in the corresponding Lazio vs Inter Milan fixture last season in October.
Meanwhile, Inter was a 2-1 winner at home last January.
We love this game 🖤💙 https://t.co/JETKyXoYvq
— Inter ⭐⭐ (@Inter_en) August 24, 2022
Across the two campaigns, Inter has now won 10 of its last 11 Serie games.
It has also won its last three away games in the competition.
However, it has not won four successive away matches since April 2021.
Lazio has won two and drawn once in its last three home games against Inter.
Lazio vs Inter Milan Pick
A bold option in Lazio vs Inter Milan would be to go for Sergej Milinkovic-Savic to score first at +900.
But this is going to be tight and it may be Lukaku who is the most powerful goal-scoring force on the pitch – and the most likely to be on target first.
Pick: Romelu Lukaku to score first (+300)
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Sports Writer
John Dillon is a leading member of the UK's sporting media, having spent three decades as a national newspaper soccer and sports writer, broadcaster and author. He has covered five World Cups, six European Championships and was Chief Sports Writer at the Daily Express for 14 years.