Arsenal vs Southampton Prediction, Odds, Lineups – Premier League Picks Week 32

• It’s Arsenal vs Southampton in the EPL Matchday 32 on Friday, April 21
• Arsenal still lead the EPL but after two consecutive draws their title hopes are wobbling
• Find our prediction below, where we look at the odds and offer some picks

It’s Arsenal vs Southampton in round 32 of the English Premier League on Friday, April 21. It all kicks off in the Emirates Stadium at 3:00 pm ET.

Arsenal still lead the EPL but their title challenge is wobbling after two consecutive 2-2 draws, both games being drawn from a 2-0 winning position, while the Saints are rooted to the foot of the table. The hosts start as massive odds-on favorites but are they the best bet for your Arsenal vs Southampton prediction?

We preview our Arsenal vs Southampton picks, look at the odds, and offer some analysis, team news, and predictions below.

Arsenal vs Southampton Odds

The bookmakers have Arsenal listed as huge odds-on favorites at -550 with an implied home win probability of 84.6%, while, on the flip side, Southampton are on offer at +1500 with a win probability of 6.3%. The draw is priced at +650 in the Arsenal vs Southampton odds and is implied at 13.3%.

Odds from DraftKings Sportsbook on April 20.

Arsenal vs Southampton Over/Under and Spread

With the benchmark set at 3.5 goals, the bookies have listed the under at -155 and the over at a more tempting +125. Based on the fact that Arsenal games have averaged 3.4 goals and Saints are bottom, this is worth considering.

Arsenal vs Southampton Preview

Two draws in their last two games have slowed down Arsenal’s title charge and with seven games to go their lead over Man City is down to just four points, with City also having a game in hand. To add to the potential drama, Arsenal head to the Etihad next Wednesday for what may well be a title decider.

Mikel Arteta’s men, while no doubt gutted that they have dropped four points in their last two games, will also know that both games were there for the taking after they made blistering starts in both. Against Liverpool and West Ham – both away from home – the Gunners went flying out of the blocks to take 2-0 leads only to be pegged back.

Setting sights on Southampton 👊

📍 London Colney pic.twitter.com/vmjotRx31e

— Arsenal (@Arsenal) April 19, 2023

Big Test for Arteta’s Men

As a result, doubts have been cast over the mental toughness of Arteta’s men who can now ill afford any more slips ups and will likely have to go to the Etihad and win in order to give themselves a chance of claiming their first title since 2003-04.

But, the Gunners have had difficult moments so far in this title charge and managed to overcome them, and will consider a visit by bottom-of-the-table Southampton as the perfect opportunity to return to winning ways.

Managerial Merry-Go-Round at Southampton

For the Saints of Southampton, this season is slowly turning into a nightmare. They have won just two of their last ten and after losing 2-0 at home to fellow strugglers Crystal Palace at the weekend, they are now marooned at the bottom of the table, two points adrift of 19th-placed Leicester City and four behind 18th-placed Nottingham Forest.

The Saints’ board’s decision to replace head coach Ralph Hasenhuttl backfired as his replacement Nathan Jones lasted just 94 days before he too was replaced by Spaniard, Ruben Selles, whose contract now takes him through to the end of the season. Selles’ first game in charge was an impressive win over Chelsea but it’s been downhill ever since.

Ready for battle 👊 pic.twitter.com/XqzWz9YMGN

— Southampton FC (@SouthamptonFC) April 15, 2023

Goals in Short Supply For Saints

Goals have been very hard to come by for the Saints all season, with just 24 in their 31 games – the joint worst in the EPL alongside Everton and Nottingham Forest.

On that basis, it’s hard to see them making too much impression against an Arsenal defense that has conceded less than a goal a game, although the Gunners are currently missing William Saliba, which may offer Southampton a faint glimmer of hope.

Arsenal vs Southampton Team Lineups and Injuries

Arsenal Projected Lineup: Ramsdale, Tierney, Gabriel, Holding, White, Ødegaard, Partey, Xhaka, Saka, Martinelli, Jesus.

Injuries & absences: Tomiyasu, Saliba, Zinchenko, Elneny.

Southampton Projected Lineup: Bazunu, Perraud, Bednarek, Bella-Kotchap, Walker-Peters, Djenepo, Ward-Prowse, Lavia, Sulemana, Alcaraz, Adams.

Injuries & absences: Salisu, Orsic, Livramento, Larios.

Arsenal vs Southampton Head-to-Head Stats

* Stats from EPL Official site.

Arsenal vs Southampton Prediction

The only scenario here where the Saints can get a result appears to be them grabbing an early goal and then defending for all their worth to withstand the Gunners’ onslaught – but it feels unlikely. With so much on the line, Arteta’s men have to find a way.

With there being little value in predicting the home win, for me, the value lies with predicting over 3.5 goals as the Gunners get their title challenge back on track.

Arsenal vs Southampton Picks: Over 3.5 goals (+125)