Opening NFL Week 1 Odds – Updated Point Spread, Moneyline, Total for All 16 Games

• With preseason in the books, the NFL Week 1 odds for all 16 games have been posted/updated
• The season opens with the Baltimore Ravens vs Kansas City Chiefs on Thursday Night Football on Sep. 5
• See the opening NFL Week 1 odds, spread, game totals, and moneyline prices for all games

The 2024 NFL preseason is in the books and we are now ten days out from the official start to the 2024 NFL regular season. Week 1 opens with the Baltimore Ravens visiting the defending Super Bowl-champion Kansas City Chiefs on Thursday Night Football on September 5. The Chiefs, who are +517 favorites on average in the Super Bowl odds, are modest three-point home favorites against the Ravens, who are +933 third-favorites.

Week 1 also sees the next iteration on the NFL International Series with the Green Bay Packers and Philadelphia Eagles meeting on Friday, Sep. 6, in Sao Paolo, Brazil.

The table below lists the opening odds for all 16 Week 1 NFL games in chronological order, culminating with Aaron Rodgers and the New York Jets visiting Brock Purdy and the San Francisco 49ers on Monday Night Football.

NFL Week 1 Odds (2024)

The prevailing theme in the Week 1 NFL odds is parity. All but three games have a spread of 4.5 points or fewer. The game totals skew to the low end with only five over/unders higher than 46.5.

Odds as of August 26 at FanDuel. New bettors can read the SBD guide How to Bet on NFL Games to get ready for Week 1. 

Biggest NFL Week 1 Spread: Patriots vs Bengals (-9.5)

The biggest spread in the NFL Week 1 odds comes from the New England Patriots vs Cincinnati Bengals game. Joe Burrow and the Bengals are massive 9.5-point home favorites.

With Burrow limited to half a season due to a wrist injury last year, Cincinnati still managed to go 9-8 last year, missing the postseason by just a game. The year prior – with a fully healthy Burrow – the Bengals went 12-4. The Patriots, meanwhile, went 4-13 last season and still haven’t officially named their Week 1 starting QB. The job will likely go to journeyman Jacoby Brissett, but rookie third-overall pick Drake Maye is also an option, especially if Brissett’s recent shoulder injury lingers.

The Patriots, who finished with the fourth-worst point differential in the league last year (-130) and tied Carolina for fewest points scored (236), used their first five picks in the 2024 draft on offense. While that should lead to a little more potency with the ball, it could mean a long day for a middling New England defense, which will have to find ways to contain Ja’Marr Chase, Tee Higgins, and newly acquired running back Zack Moss.

Highest NFL Week 1 Total: Rams vs Lions (51.5 O/U)

The largest game total on the board in Week 1 comes from the LA Rams vs Detroit Lions matchup in the Motor City, which has an O/U of 51.5, a full two points higher than any other game. (Jaguars/Dolphins is the second-highest at 49.5.) The Lions were an absolute over machine in 2023, going 13-7 O/U including the postseason. They finished fifth in the league in scoring (27.1 PPG) but had a bottom-ten scoring defense (23.2 PAPG).

Detroit made efforts to shore up its  secondary, using the #24 and #29 overall picks in the 2024 draft on cornerbacks (Alabama’s Terrion Arnold and Missouri’s Ennis Rakestraw Jr), but there is ample work to be done for a group that surrendered 7.8 yards per pass last year (second-worst in the NFL).

PUKA NACUA 1,000 YARDS ON THE SEASON ON A HOUSE CALL VS SIONE TAKITAKI pic.twitter.com/gN1FZEkxsR

— Hunter Miller (@MillerHHunter) December 3, 2023

The Rams were 9-9 O/U but that was with a ton of injuries on offense. If Matthew Stafford, Cooper Kupp, Puka Nacua, and Demarcus Robinson are all healthy – plus second-round running back Blake Corum – the Rams’ offense should look much more dynamic than it did in 2023.

This will also be LA’s first season without three-time NFL Defensive Player of the Year Aaron Donald after the 33-year-old retired in the offseason. An eight-time First Team All-Pro, Donald was still near the peak of his powers last season and is arguably the biggest defensive loss for any team heading into 2024.

Biggest Public-Betting Splits for NFL Week 1

Week 1 of every season is the only week where the public has nearly two weeks to wager on every game. The NFL public betting splits for Week 1 this season see a the public hammering a handful of teams against the spread.

The largest ATS splits so far are from the Arizona Cardinals vs Buffalo Bills, where the visiting Cardinals are getting 82% of ATS handle as 6.5-point underdogs, and the Jacksonville Jaguars vs Miami Dolphins, where the hometown Phins are getting 82% of handle as 3.5-point favorites.

The public is only backing one plus-money underdog on the moneyline, putting 84% of moneyline handle on the Dallas Cowboys as +102 road underdogs at the Cleveland Browns.

BETMGM SPORTSBOOK

Offer

T&Cs

Get Up To $1,500 Paid Back in Bonus Bets + a Second Chance TD Cash Back

21+ only. Please Gamble Responsibly. Gambling problem? Call 1-800-GAMBLER (US); 1-800-327-5050 (MA); 1-800-NEXT-STEP (AZ); 1-800-BETS-OFF (IA); 1-800-981-0023 (PR). First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Rewards are non-withdrawable bonus bets that expire in 7 days. See BetMGM.com for Terms. US promotional offers not available in MS, NY, NV, ON, or PR.

LOCK IN PROMO

CODE: DIME1500

CODE: DIME1500

SIGNUP BONUS

GET $1,500
BACK

+ 2ND CHANCE TD CASH BACK

BET NOW