NFL Preseason Week 2 Opening Odds for All Games

• The odds for Week 2 of the 2024 NFL preseason are out
• The biggest spread of the week is just 4.5 points
• See the point spread, moneyline, and total for all  games on the Week 2 preseason schedule

Week 1 of the 2024 NFL preseason is in the books and oddsmakers have already posted the lines for Week 2, which will once again see all 32 teams in action from Thursday (August 15) to Sunday (August 18).

The preseason Week 2 schedule kicks off with a Super Bowl 52 rematch when the Philadelphia Eagles visit the New England Patriots at Foxborough. It culminates with a Sunday double-header, starting with the Green Bay Packers vs Denver Broncos, which will be followed by the New Orleans Saints vs San Francisco 49ers. The other 13 games all take place on Saturday, August 17.

The table below shows the opening odds for all Week 2 preseason games, listed in chronological order. The table will be updated as more odds are released.

NFL Preseason Week 2 Odds

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Odds as of August 11 at FanDuel. Download the best football betting apps  here. 

Biggest Spread of Preseason Week 2: Texans -4.5 vs Giants

The biggest point spread on the board sees the Houston Texans laying 4.5 points at home to the New York Giants. Houston was one of the most-impressive teams during Week 1 of the preseason, cruising to a 20-12 road win at the Pittsburgh Steelers. Houston has three QBs on the roster that are vying to be CJ Stroud’s backup – Davis Mills, Case Keenum, and Tim Boyle – and all three played reasonably well in Week 1.

It was the defense that was the real MVP of the win over Pittsburgh, though, generating two takeaways (one interception and one fumble recovery), which helped Houston pitch a shutout through the first 40 minutes of the game.

The Giants also looked good in Week 1, however, breezing past the Detroit Lions 14-3 at home. Tommy DeVito was 8-of-15 for 92 yards, no TDs, and no INTs, while Drew Lock was just 4-of-10 for 17 yards and a pick in relief.

Running back Eric Gray, a 2023 fifth-round pick out of Oklahoma, scored both NYG touchdowns on the ground, finishing with 52 yards and two majors on just four carries.

Eric Gray on his own 🔥#NYGiants #NFL pic.twitter.com/xObcT5xPbx

— Top Bunk Sports (@Topbunksports) August 9, 2024

Only Four Road Teams Favored

Of the 16 games in Week 2, only four show the road team as the favorite. (Road teams went a solid 8-8 straight-up in Week 1.) In the first game of Week 2 on Thursday night, the Philadelphia Eagles are 2.5-point road favorites at the New England Patriots. The Pats were able to down the Carolina Panthers, 17-3, at home in Week 1, while the Eagles went into Baltimore and emerged with a hard-fought 16-13 win at the Ravens, erstwhile kings of the preseason.

On Saturday morning, Atlanta is a 1.5-point road favorite at those same Ravens. While Atlanta fell 20-13 at the Miami Dolphins in their Week 1 clash, rookie QB Michael Penix Jr was a standout. The former Washington Husky was 9-of-16 for 104 yards in his first taste of preseason action, including a 41-yard bomb to Chris Blair.

This 41 yard completion by Michael Penix Jr. down the sideline probably made Chris Blair feel good after his fumble.

Penix’s spiral is butter 😮‍💨pic.twitter.com/cGVNhDOOgj

— Clint Goss (@NFLDraftDome) August 9, 2024

The other two road favorites are the New York Jets laying a full field goal at the Carolina Panthers, and the LA Rams laying 1.5 at the cross-town rival LA Chargers, which is really more of a neutral-site game.