Kansas City Chiefs vs Buffalo Bills Predictions, Odds & Props (Nov. 17)

• Chiefs vs Bills NFL Week 11 odds are live
• The Kansas City Chiefs are 8-0 SU in their last eight games on the road
• Check out the latest Chiefs vs Bills odds, predictions and our best bets, below

The Buffalo Bills host the Kansas City Chiefs in Orchard Park, New York for a titanic NFL Week 11 encounter. Storylines are in abundance as Josh Allen and the Bills look to slay the dragon of Patrick Mahomes and the undefeated Chiefs. This massive AFC encounter gets underway from Highmark Stadium at 4:25 pm ET on November 17, 2024. Catch all the action over on Fox.

Until then, let’s profit! Find all the Chiefs vs Bills odds and our best bets, below.

Kansas City Chiefs vs Buffalo Bills Odds

The latest NFL odds have the Bills as 2.5-point favorites on the spread, with the Chiefs as +112 moneyline underdogs. The Chiefs vs Bills total is set at 46.5.

Odds as of November 16 at FanDuel Sportsbook. Disocver the best NFL betting apps for Chiefs vs Bills. 

Can the Chiefs stay undefeated?

Kansas City’s unblemished record is on the line against a fiery Bills squad on Sunday. The Chiefs escaped Denver with a 16-14 win after Leo Chenal blocked Will Lutz’ late field-goal attempt. However, Kansas City is dancing dangerously close to the fire. Seven of their nine contests have been one-score games, and Buffalo has the guile and talent to defeat them.

Andy Reid’s offense leads the league in third-down conversion percentage (52) and sits fourth in dropback success rate (51.5%). They’ve scored at least 26 points in four of their past five games.

Despite their lack of explosive plays, the Chiefs are finding new and innovative solutions to everything thrown at them. It may not be pretty, but they’re eking out wins like the Tom Brady-led Patriots once did.

This is why Patrick Mahomes is the most talented QB to ever play the game of American Tackle Football! #ChiefsKingdom pic.twitter.com/NnfKkD2r7Y

— Tyler Jones (@TylerJonesLive) November 10, 2024

Additionally, Patrick Mahomes is an unreal 12-1-1 ATS and 11-3 SU as an underdog in his career. Plus, the Chiefs have covered the spread in each of their four road games this season, and are 6-1-1 ATS in their last eight road games.

Is this the year the Bills finally get over the hump?

Meanwhile, Sean McDermott’s Bills are looking to prove they belong with the NFL’s elite. Win and the Buffalo Bills are a certified Super Bowl contender. Lose and Buffalo will have fallen to both the Ravens and Chiefs. Two teams they will have to go through on any path to a Super Bowl.

The scars of yesteryear undoubtedly haunt the Bills. Buffalo’s blowout loss to Kansas City in the 2021 playoffs, followed by the tormenting 13-second trauma, and last year’s Divisional Round loss on this same field are enough to give any Bills fan nightmares.

This Week 11 contest offers Allen and the Bills a golden opportunity to show they’ve overcome past playoff heartbreaks.

That Josh Allen guy is pretty good (also started Mack Hollins in a deep fantasy league) pic.twitter.com/uVsnLNhCiw

— Nick (@HolzSportsCo) November 10, 2024

Buffalo’s defense will need to generate pressure with their front four without leaving their secondary exposed. However, Buffalo sits just 15th in ESPN’s pass-rush win rate. They’ll need to pressure Mahomes to have any shot to win on Sunday.

Intriguingly, Josh Allen and the Bills have won three straight regular-season contests against Kansas City. They’ve also covered the spread in all four home games at Highmark Stadium this season. But, the question remains: can they finish the job in big games?

Kansas City Chiefs vs Buffalo Bills Prediction

This clash of AFC heavyweights has all the makings of an instant classic. With DeAndre Hopkins and Kareem Hunt in tow, and Travis Kelce looking like his old self, Mahomes is armed with a three-headed arsenal primed to break down even the best defenses.

Allen and the Bills have scored 30-plus points in four straight games. He’s consistently moved the football and has the ability to crack the code of Steve Spagnuolo’s heavy man-blitzing scheme.

Ultimately, Chiefs vs Bills is too close to call. Expect a tight game that comes down to key plays late in the fourth quarter. With that being said, these elite quarterbacks will push the game towards the over. Both the Bills and Chiefs boast a ton of playmakers, and with Mahomes and Allen pulling the strings, there will be fireworks.

• Chiefs vs Bills Pick: Over 46.5 (-108)