NFL Draft Odds to Be First & Second Player Picked at Each Position

• The 2025 NFL Draft starts tonight in Green Bay, WI
• Cam Ward and Ashton Jeanty are heavy favorites to be the first QB and WR selected
• See the odds to be the first and second player picked at every position

The first round of the 2025 NFL Draft goes tonight near Lambeau Field in Green Bay, Wisconsin. Coverage will start at 8:00 pm ET and there is no shortage of NFL Draft props available for bettors. DraftKings has posted odds on which players will be selected first (and, in most cases, second) at almost every position on the field.

Use the following links to jump directly to the position you’re interested in:

Quarterbacks | Running Backs | Wide Receivers | Tight Ends | Cornerbacks | D-Linemen | O-Linemen | Safeties

First & Second QB Picked Odds

All odds from DraftKings at 7:30 am ET, April 24. Find the best betting app for the 2025 NFL Draft.

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Colorado QB Shedeur Sanders opened as the favorite to be the #1 pick in the NFL Draft odds last April and maintained that status until the calendar flipped to 2025. But that’s when Miami pivot Cameron Ward inched past him and never looked back.

Now Ward is a prohibitively short -20000 to be the first QB selected in the 2025 draft. The more interesting question has become: will Shedeur even be the #2 pick? He’s a -195 favorite in that market with Ole Miss QB Jaxson Dart just behind him at +165.

First & Second Running Back Drafted Odds

The odds to be the first running back off the board also have a massive favorite: Boise State’s Ashton Jeanty, who is -20000, same as Ward in the QB props.

When it comes to the second RB, North Carolina’s Omarion Hampton is the chalk at -230. Matt McEwan’s latest NFL mock draft has Hampton as the only other running back going in the first round (#20 to the Denver Broncos).

Ohio State’s TreVeyon Henderson is seen as the only real competition to Hampton, priced at +175 to be the second running back off the board. Most mock drafts have the former Buckeye going in the second round.

First & Second Wide Receiver Picked Odds

The first WR odds continue to favor Arizona’s Tet McMillan but, at -290, there’s still considerable doubt. The other potential first WR off the board is Texas wideout Matthew Golden, who is +200 to be the first WR picked and the -180 favorite to be the second.

The clear third choice on draft boards is Ohio State’s Emeka Egbuka, who is priced at +1600 to be the first WR selected and +320 to be the second.

First Tight End Drafted Odds

The odds to be the first tight end selected in the 2025 NFL draft heavily favor Penn State’s Tyler Warren at -450, which amounts to an 81.8% implied probability. The only other plausible choice according to oddsmakers is Michigan TE Colton Loveland, who has +280 odds (26.3%). No other tight end is shorter than +10000.

SBD’s mock draft has Warren going #10 to the Colts (via trade with the Bears) and Loveland going #14 to the Bears with the Colts’ pick.

First & Second Cornerback Selected Odds

Dual-threat CB/WR Travis Hunter is being treated exclusively as a corner inat DraftKings and, as such, is a heavy favorite to be the first CB chosen in the 2025 NFL draft. SBD’s latest mock draft has Hunter going second overall to the Browns, and then no other corners until #13.

Michigan’s Will Johnson is SBD’s second corner off the board but the betting odds slightly favor Texas Longhorn Jahdae Barron (-110) over Johnson (+140).

First & Second D-Lineman Drafted Odds

The defensive lineman/edge rusher market is another where there is a massively-short favorite. This time, it’s Penn State edge rusher Abdul Carter (-20000). Carter is also the -800 favorite to be the third-overall pick to the Giants (or whoever trades into that spot).

Curiously, Michigan DT Mason Graham is the second-favorite at +4000 but he’s not favored to be the second DL picked. That honor belongs to Georgia’s Mykel Williams, who is the -200 favorite with Graham second at +250.

First Offensive Lineman Drafted Odds

LSU’s Will Campbell is the -1400 favorite to be the first offensive lineman picked on Thursday night, which is a 93.3% implied probability. Campbell is the -475 chalk to be the #4 pick to the Pats.

SBD’s mock draft has two other OL going in the first 15 picks: Missouri’s Armand Membou at #7 to the Jets and Texas’ Kelvin Banks Jr at #11 to the 49ers.

First Safety Drafted Odds

The odds to be the first safety picked in 2025 slightly favor Georgia’s Malaki Starks (-155) over South Carolina’s Nick Emmanwori (+125). Both are expected to be first-round picks and SBD’s mock projects Starks to the Vikings at #24 and Emmanwori to the Bills at #30.

No other safety’s project as first-round pick. Xavier Watts is third on the odds board but at a distant +4000.