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Buffalo Bills vs New York Jets Odds, Lines, Picks and Predictions for Week 1 Monday Night Football

Robert Duff

by Robert Duff in NFL Football

Updated Sep 10, 2023 · 4:15 PM PDT

Josh Allen and the Buffalo Bills are road favorites over Sauce Gardner and the New York Jets on MNF
Dec 11, 2022; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) runs the ball against New York Jets cornerback Sauce Gardner (1) in the second quarter at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports
  • The Buffalo Bills are 2-point road favorites over the New York Jets in this Week 1 MNF game between these AFC East rivals on September 11
  • Buffalo is 7-3 straight up in the last 10 games against the Jets
  • See the Bills vs Jets predictions, odds, and betting picks for Monday Night Football

All eyes will be on the MNF opener as Aaron Rodgers makes his debut with the New York Jets, leading them out to face the beasts of the AFC East, the Buffalo Bills. The offseason addition of four-time NFL MVP Rodgers to run the New York offense has many speculating that they could upend the Bills and win the division title.

This Week 1 clash on prime time TV is offering both of these teams the perfect opportunity to post a statement victory. It’s the Bills that oddsmakers are setting as 2-point road favorites for the game. Buffalo is 5-1 straight up over the last six meetings with the Jets.

Let’s look deeper into the Bills vs Jets odds before offering you our prediction for this NFL Week 1 MNF game.

Bills vs Jets Odds

Team Moneyline Spread Total
Buffalo Bills -126 -2 (-126) Over 45.5 (-110)
New York Jets +108 +2 (-108) Under 45.5 (-110)

In the Bills vs Jets odds, the Bills are -126 moneyline favorites, giving them a 55.75% implied win probability. The total is set at 45.5 points. In three of the last four times Buffalo played the Jets on the road, the total went under.

Odds as of September 10 at FanDuel Sportsbook. Be sure to claim a FanDuel promo code to bet on Bills vs Jets or check out the wide list of NFL player props available. 

The Jets are 3-3 against the spread in the last six games against Buffalo. Winners at home in last year’s meeting, they haven’t won back-to-back home games against the Bills since 2016-17.

Kickoff for this game at MetLife Stadium on Monday, September 11, is set for 8:15pm ET. The broadcast is being carried by ESPN and by DAZN in Canada.

Bills vs Jets Betting Splits

In the NFL public betting trends, moneyline bettors are in love with Buffalo, while spread bettors are in a New York state of mind. In spread splits, the underdogs from New York are pulling 82% of handle and 94% of bets. The Jets are 1-5 ATS in their last six games. It’s the favored Bills who are getting 67% of handle and 80% of bets in moneyline splits. Buffalo is 8-1 SU in the last nine games.

The over is popular in total splits. It’s taking 67% of handle and 72% of bets in the Bills vs Jets picks. The under is 3-0 in the last three games between these teams.

Buffalo is the fourth betting choice in the Super Bowl odds at +900. The Jets are seventh overall in this betting market with a line of +1600.

Buffalo vs NY Jets Injuries

Placed on the PUP list with a knee injury, Bills RDE Von Miller will be out until at least Week 5. Buffalo RB Nyheim Hines is out after undergoing reconstructive ACL surgery.

For the Jets, RB Breece Hall (knee) is listed as questionable, but is expected to play. Both starting tackles – LT Duane Brown (shoulder) and RT Mekhi Becton (illness) – are also showing on the injury report as questionable.

Best Jets Team Ever?

Former NFL coach Rex Ryan is touting the 2023 edition of the Jets as listing the most talented roster in the history of the franchise. Along with Rodgers, other additions included multiple 1,000-yard rusher Dalvin Cook. There’s NFL OROY Garrett Wilson at WR and NFL DROY Sauce Gardner at CB.

Ryan is calling the Jets to win the Super Bowl. Now an analyst for ESPN, Ryan might be a bit biased. He coached the Jets to two AFC Championship games during his tenure as head coach of the team from 2009-14.

Bills Have Something to Prove

While Buffalo has won three successive AFC East titles, the Bills still haven’t got back to the Super Bowl since the 1990s. Buffalo will be debuting a new feature back. James Cook is replacing the departed Devin Singletary. He’s Dalvin Cook’s younger brother.

One thing Rodgers may have to worry about is that for the first time since 2021, Micah Hyde, Jordan Poyer and Tre’Davious White are all healthy and slated to start in the Buffalo secondary. Each of this trio has been to the Pro Bowl.

Bills vs Jets Prediction

During his time with Green Bay, Rodgers was 2-0 SU and ATS against Buffalo. But you can be sure the Bills have been targeting this game from the moment the Rodgers hype machine switched on. Buffalo is 7-3 SU in the last 10 games against the Jets. Just one of those losses came at MetLife Stadium.

Bills vs Jets Pick: Buffalo Bills -2 (-110)

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