NFL Draft Day 2 Predictions & Odds – How Long Does Shedeur Sanders Stay on the Board?

• Day 2 of the NFL Draft goes Friday from Green Bay, Wisconsin
• Big 12 Player of the Year Shedeur Sanders is still on the board, among other valuable star-caliber players
• See the best Day 2 NFL Draft Bets and Picks, below

---

The first round of the NFL Draft is in the books, but the real maneuvering is only just beginning.

Yes, most of the blue-chip prospects had their dreams realized on Thursday night, but there are so many top end, plug-and-play starters still waiting to get called, and perhaps some of them now carrying a mighty chip on their shoulder.

So it’s time for us to dig into the rest of the best in the NFL Draft odds, sharing some of the best you should be considering when Day 2 of the NFL Draft goes at 7pm ET from Green Bay.

Odds to Be #33 Overall Pick

Well, the Cleveland Browns have plenty to think about, as there are a bevy of stars sitting there for the taking, including Shedeur Sanders, a one-time Top 5 pick that has slipped out of the first round entirely. Alabama QB Jalen Millroe is there as well, and so is BC edge rusher Donovan Ezeiruaku.

Odds as of April 25th at FanDuel. Claim the FanDuel promo code before making any NFL Draft bets.

NFL Draft Round 2 Pick #1: Browns End Sanders Saga

Depending on what the Browns want, the NFL Draft couldn’t have set up better for them.

First, they deal the second pick to the Jaguars to pick up some valuable draft capital and still having a Top-5 pick, which they used to take defensive tackle Mason Graham. The Michigan product will work the interior while Myles Garrett continues to wreak havoc from the outside.

With that defensive line set up for now and the future, two legit signal callers are right there for the taking.

If somebody tells you Shedeur Sanders doesn’t do anything special, just know they are full of it and haven’t watched his tape. That’s just pure hate and hopping on a narrative tearing him down for clicks. So tired of hearing it. pic.twitter.com/3qvPKKgi9Z

— Robert Griffin III (@RGIII) April 25, 2025

Shedeur Sanders has somehow fallen out of Round 1 all together, joined by Alabama’s Jalen Milroe. Cleveland has Kenny Pickett and Joe Flacco in its QB room, so maybe a potential franchise cornerstone could lighten up that outlook.

Kevin Stefanski can work wonders with either of these prospects, or even Louisville pivot Tyler Shough, if the Browns feel so inclined.

Either way, a QB is coming off the board first to kick off Round 2.

• Shedeur Sanders to be a the 33rd Pick (-155 at FanDuel)

Odds to Draft Cam Skattebo

Odds as of April 25th at DraftKings. Claim the DraftKings promo code before making any NFL Draft bets.

NFL Draft Day 2 Pick: Steelers Snag Skattebo

Besides the anticipated fall of Sanders, one of the other not-so-subtle stories was where Arizona State stud running back Cam Skattebo was going to end up.

Mind you. there are still three other running backs ahead of him — a list that includes Ohio State standout TreVeyon Henderson — but there’s almost no chance Skattebo now falls to Day 3 of the NFL Draft.

Best Running Backs Available 2025 NFL Draft

A transfer from Sacramento State, Skattebo was a standout for Arizona State in 2024, producing over 2,300 scrimmage yards and finding the endzone 24 times, which was tops in the Big 12.

He’s definitely not the fastest of the running backs still on the board, but he’s explosive and most of all, talented and tough.

Notice the names at the top of the odds board that are favored to nab him in the draft, and the one trait they have in common is their ability to find value at that running back position later on down the line in the Draft.

The Patriots have the earliest shot at him with the 38th pick, but I think he’s going at a late pull in the second round, if not early in the third.

Kansas City lurks at the bottom of Round 2 with the 63rd pick and are near the top of Round 3 with the 66th pick, while Kyle Shanahan and the 49ers lurk at the 75th pick. Still, Skattebo feels like a Pittsburgh Steelers kind of grab, and with Najee Harris now with the Chargers, there’s an opening for a tough runner in Mike Tomlin’s backfield, assuming he is still there with the 83rd pick.

• Pittsburgh Steelers to draft Cam Skattebo (+1200 at FanDuel)