White Sox vs Astros Picks & Odds (March 31)

By John Perrotto in MLB Baseball
Published:

- The Astros are -155 home favorites over the White Sox on Friday night
- Lance Lynn will pitch for the White Sox against the Astros’ Cristian Javier
- A look at the White Sox vs Astros odds can be found below with a pick
The Chicago White Sox and Astros play the second game of their season-opening four-game series at 8:10 p.m. ET Friday at Minute Maid Park in Houston.
In Thursday night’s season opener, the White Sox edged the Astros 3-2. That ended Houston’s streak of 10 consecutive wins on opening day.
MLB Network will televise the game.
White Sox vs Astros Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
Chicago White Sox | +125 | +1.5 (-160) | Over 7.5 (-115) |
Houston Astros | -155 | -1.5 (+135) | Under 7.5 (-105) |
The Astros are -155 favorites over the White Sox in the MLB odds, giving them a 60.78% implied win probability. Houston is the +600 favorite to repeat as champion in the World Series championship odds while Chicago is listed at +4000.

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Odds as of March 30th at BetMGM.
White Sox vs Astros Probable Pitchers
Lance Lynn (8-7, 3.99 in 2022) is scheduled to pitch for the White Sox against Cristian Javier (11-9, 2.54).
Lynn vs Javier
8-7 | Record | 11-9 |
3.99 | ERA | 2.54 |
3.62 | xERA | 2.43 |
1.13 | WHIP | 0.95 |
6.53 | SO/W | 3.73 |
Lynn has had mixed results in his career against the Astros, going 5-7 with a 4.41 ERA in 14 games (13 starts).
Last season, he went 4-4 with a 3.95 ERA in 12 road starts. He was 2-4 with a 4.15 ERA in 11 starts at night.
Lynn worked 14.2 innings in the Cactus League this spring, surrendering seven runs and 16 hits. He also had 18 strikeouts and four walks.
Javier has faced the White Sox only once and was sharp in that start in 2022 as he yielded one run in five innings to get the win.
Cristian Javier's 3Ks thru 2. pic.twitter.com/9z5PAgKzrZ
— Rob Friedman (@PitchingNinja) March 19, 2023
Javier was 6-5 with a 2.26 ERA in 15 games (12 starts) at Minute Maid Park last season. He had a 7-7 record and a 3.17 ERA at night in 20 games (17 starts).
During spring training, Javier – who has +2400 AL Cy Young Award odds — gave up three runs on 10 hits in 11.2 innings while striking out 10 and walking one.
Batting Average vs Starting Pitchers
White Sox Batters | Batting Average vs Javier |
---|---|
Elvis Andrus | .333 |
Luis Robert Jr. | .333 |
Andrew Benintendi | .000 |
Andrew Vaughn | .000 |
Astros Batters | Batting Average vs Lynn |
Martin Maldonado | .500 |
Yordan Alvarez | .455 |
Alex Bregman | .400 |
Kyle Tucker | .200 |
Jose Abreu | .191 |
Chas McCormick | .000 |
White Sox second baseman Elvis Andrus is 4 for 12 (.333) versus Javier and all the hits have been for extra base – three doubles and one home run.
Astros catcher Martin Maldonado is a .500 hitter (7 for 14) against Lynn with one double and a homer. First baseman Jose Abreu is just 4 for 21 (.191) versus and joined the Astros as a free agent in the offseason after spending his first nine major-league seasons with the White Sox.
Astros vs White Sox Betting Trends
Andrew Vaughn snapped a 1-1 tie with a two-run double in the top of the ninth Thursday to the White Sox to victory.
Chicago withstood Yordan Alvarez’s solo home run in the bottom of the inning. The slugging first baseman has +1200 AL MVP odds.
Andrew Vaughn. CLUTCH! pic.twitter.com/7Zt9cpiJ9Y
— Chicago White Sox (@whitesox) March 31, 2023
Yasmani Grandal accounted for the White Sox’s other run with a homer. Tim Anderson and Luis Robert Jr. had two hits each.
The Astros managed just four hits and struck out 13 times.
Astros vs White Sox Last 10 Games
Date | Home Team | Away Team | Score |
---|---|---|---|
3/30/22 | Astros | White Sox | CWS, 3-2 |
8/18/22 | White Sox | Astros | HOU, 21-5 |
8/17/22 | White Sox | Astros | HOU, 3-2 |
8/16/22 | White Sox | Astros | CWS, 4-3 |
8/15/22 | White Sox | Astros | CWS, 4-2 |
6/19/22 | Astros | White Sox | HOU, 4-3 |
6/18/22 | Astros | White Sox | CWS, 7-0 |
6/17/22 | Astros | White Sox | HOU, 13-3 |
10/12/21 | White Sox | Astros | HOU, 10-1 |
10/10/21 | White Sox | Astros | CWS, 12-6 |
The Astros were 22-10 against the White Sox during the previous four seasons from 2019-22. That included Houston beat Chicago in four games in an American League Division Series in 2021.
White Sox vs Astros Prediction
Javier quietly had an outstanding 2022 then allowed only one run in 12.2 innings in the postseason as the Astros won the World Series. Look for him to carry over that strong performance to his first start of the new season.
Pick: Astros moneyline (-155)
Season Record: 0-1 (-1.4 units) ML

Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.