
Orioles vs Red Sox Odds, Spread & Predictions (April 1)

By John Perrotto in MLB Baseball
Published:

- The Red Sox are -155 home favorites over the Orioles on Saturday
- Dean Kremer will pitch for the Orioles against Red Sox left-hander Chris Sale
- A look at the Orioles vs Red Sox matchup and odds can be found below with a pick
After a wild season opener Thursday and a day off Friday, the visiting Baltimore Orioles and Boston Red Sox resume their three-game series at 4:10pm ET Saturday at Fenway Park.
The Orioles outlasted the Red Sox 10-9 on Thursday.
Orioles vs Red Sox Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
Baltimore Orioles | +135 | +1.5 (-135) | Over 9 (-110) |
Boston Red Sox | -155 | -1.5 (+115) | Under 9 (-110) |
The Red Sox are -155 favorites over the Orioles on the moneyline in the MLB odds, giving them a 60.78% implied win probability. Boston has +6000 World Series championship odds and Baltimore is listed at +8000.


Odds as of March 31st at DraftKings. See the latest on Massachusetts sports betting.
Orioles vs Red Sox Probable Pitchers
Dean Kremer (8-7, 3.23 in 2022) is scheduled to start for the Orioles against left-hander Chris Sale (0-1, 3.18 in 2022).
Kremer vs Sale Head-to-Head
8-7 | Record | 0-1 |
3.23 | ERA | 3.18 |
4.46 | xERA | 4.08 |
1.25 | WHIP | 1.06 |
2.56 | SO/W | 5.00 |
Sale was limited to just two starts last season while recovering from Tommy John surgery as well as suffering other injuries.
In 23 career games (17 starts) against the Orioles, Sale has a stellar 10-3 record with a 2.71 ERA.
Sale did not pitch at Fenway Park last season. In his one game during the day, he gave up three runs (two earned) in 0.2 innings and took the loss.
Sale pitched 15 innings during Grapefruit League play in spring training. He gave up eight runs on 17 hits with 12 strikeouts and three walks.
Chris Sale. ⛽️ pic.twitter.com/iAMOcQrUnb
— Rob Friedman (@PitchingNinja) March 6, 2023
Despite coming off a lost season, Sale is listed in the AL Cy Young odds at +7000.
The Red Sox have been Kremer’s nemesis as he is 0-4 in his career against them with a 6.85 ERA in five starts.
In 2022, Kremer was 5-3 with a 3.63 ERA in 11 starts on the road. In day games, he went 2-2 with a 4.76 ERA in seven outings.
Kremer had 16 strikeouts and just three walks in 18.2 innings this spring but also allowed 10 runs and 16 hits.
Batting Average vs Starting Pitchers
Orioles Batters | Batting Average vs Chris Sale |
---|---|
Adam Frazier | .500 |
Austin Hays | .273 |
Ryan McKenna | .200 |
Ryan Mountcastle | .200 |
Anthony Santander | .167 |
Cedric Mullins | .125 |
Jorge Mateo | .000 |
Ramon Urias | .000 |
Red Sox Batters | Batting Average vs Dean Kremer |
Rob Refsnyder | 1.000 |
Alex Verdugo | .357 |
Rafael Devers | .273 |
Christian Arroyo | .250 |
Enrique Hernandez | .250 |
Reese McGuire | .000 |
Triston Casas | — |
Orioles star center field Cedric Mullins has only one hit in eight at-bats against Sale. Red Sox right fielder Alex Verdugo is 5-for-14 (.357) with two doubles and a home run off Kremer.
Orioles vs Red Sox Betting Outlook
Adley Rutschman became the first catcher in major league history with five hits in an opener while leading the Orioles to victory Thursday.
Rutschman, who has +3000 AL MVP odds, homered in his first at-bat and finished 5-for-5 with a career-best four RBIs and a walk. Ramon Urias hit a two-run homer for the Orioles, who finished with 15 hits, nine walks and five stolen bases.
ADLEY RUTSCHMAN JUST HOMERED ON HIS FIRST OPENING DAY!!! pic.twitter.com/jsnKMuvW1e
— Baltimore Orioles (@Orioles) March 30, 2023
Anthony Santander, Adam Frazier and Julio Mateo had two hits each for the Orioles.
The Red Sox’s Rafael Devers became the first player in major league history to be called out for a pitch clock violation. Verdugo, Devers, Justin Turner and Masataka Yoshida had two hits apiece.
Orioles vs Red Sox Last 10 Games
Date | Home Team | Away Team | Score |
---|---|---|---|
3/30/23 | Red Sox | Orioles | BAL, 10-9 |
9/29/22 | Red Sox | Orioles | BOS, 5-3 |
9/28/22 | Red Sox | Orioles | BOS, 5-1 |
9/27/22 | Red Sox | Orioles | BOS, 13-9 |
9/26/22 | Red Sox | Orioles | BAL, 14-8 |
9/11/22 | Orioles | Red Sox | BOS, 1-0 |
9/10/22 | Orioles | Red Sox | BOS, 17-4 |
9/9/22 | Orioles | Red Sox | BAL, 3-2 |
8/21/22 | Orioles | Red Sox | BAL, 5-3 |
8/20/22 | Orioles | Red Sox | BOS, 4-3 |
Orioles vs Red Sox Prediction
Sale has been limited to 48.1 innings over the last three seasons and it is impossible to know if he will ever return to his All-Star former self. However, his healthy spring coupled with Kremer’s troubles with the Red Sox make Boston the play here.
Pick: Red Sox -155 ML
Season Record: 0-1 (-1.4 units)

Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.