MLB Opening Day Odds for All 15 Games

By Sascha Paruk in MLB Baseball
Published:

- Thursday, March 30, marks MLB Opening Day for the 2023 season
- Not a single MLB Opening Day run total is in double digits
- Below, see the MLB Opening Day odds (moneyline, runline, and over/under) for all 15 games
The 2023 MLB season officially gets underway at 1:05 pm ET on Thursday, March 30, with a pair of games: Atlanta Braves vs Washington Nationals, and San Francisco Giants vs New York Yankees.
But those are just two of the 15 games on Opening Day, meaning all 30 teams in Major League Baseball will be in action on Thursday.
The table below shows the odds (moneyline, runline, and over/under run total) for all 15 games on the docket.
MLB Opening Day Odds 2023
Matchup | Moneyline | Runline | Total |
---|---|---|---|
Braves | -255 | -1.5 (-145) | O 8 (-105) |
Nationals | +215 | +1.5 (+125) | U 8 (-115) |
Matchup | Moneyline | Runline | Total |
Giants | +155 | +1.5 (-145) | O 7 (-125) |
Yankees | -180 | -1.5 (+125) | U 7 (+105) |
Matchup | Moneyline | Runline | Total |
Orioles | +105 | +1.5 (-180) | O 9 (-110) |
Red Sox | -125 | -1.5 (+155) | U 9 (-110) |
Matchup | Moneyline | Runline | Total |
Brewers | -140 | -1.5 (+120) | O 7.5 (+100) |
Cubs | +120 | +1.5 (-140) | U 7.5 (-120) |
Matchup | Moneyline | Runline | Total |
Tigers | +195 | +1.5 (-115) | O 6.5 (-120) |
Rays | -230 | -1.5 (-105) | U 6.5 (+100) |
Matchup | Moneyline | Runline | Total |
Phillies | +115 | +1.5 (-205) | O 6.5 (-120) |
Rangers | -135 | -1.5 (+175) | U 6.5 (+100) |
Matchup | Moneyline | Runline | Total |
Twins | -155 | -1.5 (+105) | O 9 (+100) |
Royals | +135 | +1.5 (-125) | U 9 (-120) |
Matchup | Moneyline | Runline | Total |
Mets | -125 | -1.5 (+150) | O 6.5 (-115) |
Marlins | +105 | +1.5 (-175) | U 6.5 (-105) |
Matchup | Moneyline | Runline | Total |
Pirates | +120 | +1.5 (-165) | O 8.5 (-105) |
Reds | -140 | -1.5 (+145) | U 8.5 (-115) |
Matchup | Moneyline | Runline | Total |
Blue Jays | -115 | -1.5 (+145) | O 7.5 (-110) |
Cardinals | -105 | +1.5 (-170) | U 7.5 (-110) |
Matchup | Moneyline | Runline | Total |
White Sox | +135 | +1.5 (-165) | O 7.5 (+105) |
Astros | -155 | -1.5 (+140) | U 7.5 (-125) |
Matchup | Moneyline | Runline | Total |
Rockies | +180 | +1.5 (-120) | O 7.5 (-120) |
Padres | -210 | -1.5 (+100) | U 7.5 (+100) |
Matchup | Moneyline | Runline | Total |
Angels | -210 | -1.5 (-120) | O 7 (-115) |
Athletics | +180 | +1.5 (+100) | U 7 (-105) |
Matchup | Moneyline | Runline | Total |
Guardians | +100 | -1.5 (+185) | O 6.5 (-125) |
Mariners | -120 | +1.5 (-215) | U 6.5 (+105) |
Matchup | Moneyline | Runline | Total |
Diamondbacks | +145 | +1.5 (-140) | O 7.5 (+105) |
Dodgers | -170 | -1.5 (+120) | U 7.5 (-125) |
The day’s action wraps up with a trio of games at 7:10: Angels vs Athletics, Guardians vs Mariners, and Diamondbacks vs Dodgers. The only interleague matchup on the slate is Giants vs Yankees. Nine of the 15 games see two divisional opponents squaring off.

Odds as of 1:05 am ET, March 30, at DraftKings Sportsbook.
Biggest MLB Opening Day Favorites
Four teams currently have a moneyline at -200 or shorter. The biggest favorites on Opening Day are the Braves (-255 at the Nationals), Rays (-230 vs the Tigers), Padres (-210 vs the Rockies), and Angels (-210 at the Athletics).
In terms of projected MLB win totals, those four games are also the biggest mismatches: Atlanta’s win total (94.5) is 33 games higher than Washington’s (61.5); San Diego’s win total (92.5) is 27 games higher than Colorado’s (65.5); the LA Angels’ win total (81.5) is 21 higher than Oakland’s (60.5); and Tampa’s win total is 18 higher than Detroit’s.
Only one matchup is approaching a pick’em. The Toronto vs St Louis odds list both teams with a negative moneyline, the Blue Jays being slight -115 road favorites as of Thursday morning.
Highest and Lowest MLB Opening Day Run Totals
With aces on the mound across the nation, a number of the game totals on Opening Day are abnormally low for MLB regular-season action.
Four games feature a run total of 6.5: Tigers vs Rays (Eduardo Rodriguez vs Shane McClanahan), Phillies vs Rangers (Aaron Nola vs Jacob deGrom), Mets vs Marlins (Max Scherzer vs Sandy Alcantara), and Guardians vs Mariners (Shane Bieber vs Luis Castillo).
The over is favored in all four of those games, but the Mets/Marlins matchup has an o/u of 6.5 (-115/-105) and has been trending toward the under. Don’t be surprised if under 6.5 is the favorite come first pitch. Alcantara the reigning Cy Young-winner in the National League and enters 2023 as the co-favorite in the NL Cy Young odds alongside Milwaukee’s Corbin Burnes (2021 winner). Scherzer has three Cy Youngs under his belt and finished a close third to Burnes in 2021.
https://www.youtube.com/watch?v=RJNBy4h1MuM
Not a single Opening Day run total is in double digits. The highest total on the board is 9.0, which is shared by Orioles vs Red Sox (Kyle Gibson vs Corey Kluber) and Twins vs Royals (Pablo Lopez vs Zack Greinke).

Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.