Week 3 College Football A.I. Picks After 8-2 ATS Week
By Brady Trettenero in College Football
Updated: September 18, 2026 at 2:33 am EDTPublished:
- The model’s Week 3 college football picks cover 10 games across Friday and Saturday
- LSU at Ole Miss headlines the board after the market flipped the favorite
- See every ATS and over/under pick below, plus last week’s full results
Week 2 was the Sportradar model’s best spread week so far, finishing 8-2 ATS with a 5-5 split on totals. That puts it at 14-7 ATS and 13-8 on totals through two weeks, or 27-15 overall.
Week 3 hands it 10 games, all of them posted at the top college football betting apps. Miami at Wake Forest and Houston at Texas Tech go Friday night, with the other eight on Saturday.
All 20 model picks follow, with a closer look at three featured matchups and last week’s results.
A.I. College Football Picks for Week 3
Eight of the 10 totals picks land on the over, which is a shift from where the model sat in Week 2. Eight of the 10 sides back a favorite.
Picks recorded Thursday, September 17. The lines listed are the numbers the picks were made against and will move before kickoff, so shop around. New customers can claim the BetMGM promo code and get a bonus to bet on college football.
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LSU vs Ole Miss AI Picks
This one opened with Ole Miss favored at home. It has since crossed zero and the key number of three, with LSU now laying the points in Oxford.
LSU handled Louisiana Tech 45-14 in a game that was messier than the final. The Tigers coughed it up four times in the first half, three of those on Sam Leavitt interceptions, and still won by 31 while Leavitt threw for 381 yards.
Ole Miss took care of Charlotte 41-9 with Trinidad Chambliss going 23 of 26 for 225 yards and two scores. That was efficient work against an overmatched defense, after the Rebels opened with a 41-38 win over Louisville. The model wants LSU and the over here.
SMU vs Louisville AI Picks
SMU owns the better road win of the two. Kevin Jennings threw for 430 yards in the 27-24 win at Florida State, and the Mustangs piled up 585 total yards despite turning it over four times.
Louisville has been the cleaner team. The Cardinals put up 635 yards in a 59-13 win over Villanova, with Lincoln Kienholz going 16 of 21 for 332 yards and two touchdowns before adding two more on the ground.
Villanova is not Florida State, and that gap is why the model takes the points with SMU in a near pick-em. It also wants the over 58.5, which is fair with both quarterbacks playing this well.
Houston vs Texas Tech AI Picks
Texas Tech is 2-0 after a 35-24 win at Oregon State, but the Beavers outgained them 472-352 and threw for 417 yards. The Red Raiders won it on situational downs instead, converting eight of 16 third downs while holding Oregon State to four of 15.
Houston beat FCS Southern 77-6, which tells you very little. Conner Weigman was 9 of 12 for 120 yards and three touchdowns and was out of the game by the second quarter.
Neither team has faced much, so the model is buying the points rather than the blowout. It pairs Houston +7.5 with the under 52.5.
A.I. College Football Picks: Week 2 Results
Both losses were one-score games, with Michigan winning outright as a home dog and Texas surviving Ohio State by a point. Five of the 10 games hit both the spread and the total.
Lead NHL & NCAAF Editor
Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.
