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MLB Picks & Predictions for Wednesday Night – Best Bets for All Six Games

Sascha Paruk

By Sascha Paruk in MLB Baseball

Published:


Toronto Blue Jays relief pitcher Jacob Barnes and catcher Tyler Heineman celebrating a win
Apr 8, 2025; Boston, Massachusetts, USA; Toronto Blue Jays relief pitcher Jacob Barnes (67) and catcher Tyler Heineman (55) celebrate defeating the Boston Red Sox at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images
  • The MLB has six night games on the schedule on Wednesday, April 9
  • Headlined by the Phillies vs Braves in Atlanta, is stacked with divisional rivalries
  • See the odds and my picks and best bets for all six MLB games on Wednesday night

A full slate of 15 games in the MLB on Wednesday is capped off by six with a first pitch at 6:35 pm ET or later. With most of the day games well underway, it’s time for me to focus on the evening slate, which is replete with divisional rivalries. The table below sets out the odds (moneyline, runline, total) for all six games, along with my best bet for each one.

MLB Odds & Picks for Wednesday, April 8

MatchupMLRLO/UPick/Odds
White Sox+158+1.5 (-135)O 7.5 (-100)CLE -1.5
Guardians-190-1.5 (+115)U 7.5 (-120)+115
MatchupMLRLO/UPick/Odds
Blue Jays+110+1.5 (-190)O 8.5 (-100)TOR ML
Red Sox-130-1.5 (+158)U 8.5 (-120)+110
MatchupMLRLO/UPick/Odds
Angels+122+1.5 (-170)O 8.0 (-100)TB ML
Rays-145-1.5 (+143)U 8.0 (-120)-145
MatchupMLRLO/UPick/Odds
Phillies+115+1.5 (-170)O 8.5 (-115)ATL ML
Braves-135-1.5 (+143)U 8.5 (-105)-135
MatchupMLRLO/UPick/Odds
Twins-110+1.5 (-225)O 7.5 (-115)KC ML
Royals-110-1.5 (+185)U 7.5 (-105)-110
MatchupMLRLO/UPick/Odds
Brewers-140-1.5 (+110)O 10.5 (-115)MIL ML
Rockies+118+1.5 (-130)U 10.5 (-105)-140

Odds as of 2:20 pm ET at Caesars. Sign-up today to participate in the Caesars rewards program.

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Sascha Paruk’s 2025 MLB betting record: 9-12 (-4.48 units). All wagers one unit unless stated otherwise.

Blue Jays vs Red Sox Pick: Toronto ML

The Red Sox (6-6, 3-2 home) are proving to be the streakiest team in the majors in the early going. After starting the season 1-4, they rattled off five straight wins to get back above .500, but now they’ve dropped two straight at home to the AL East-rival Blue Jays (7-5, 2-3 away), scoring just three runs in 18 innings: 6-2 on Monday, 6-1 on Tuesday.

YouTube video

Coming off an All-Star 2024 campaign, Tanner Houck (6.52 ERA, 1.76 WHIP in 9.2 innings) has been awful in his first two starts of 2025. Yes, both were on the road, but that’s where he posted a 2.82 ERA last season, compared to a 3.33 number at home.

Kevin Gausman (3.97 ERA, 0.71 WHIP in 11.1 IP) has been considerably better, and also has a much longer track record than Houck of being an almost-elite MLB starter. He’s also had plenty of success against this current Boston roster (.230 average, .653 OPS in 135 total at-bats).

I love the Jays at plus money tonight.

  • Pick: Blue Jays moneyline (+110)

Phillies vs Braves Pick: ATL Moneyline

In the NL East battle between the Phillies (7-3, 2-2 away) and struggling Braves (2-8, 2-1 home), I’m backing Atlanta to continue righting the ship in their second homestand of the season. The Braves started the year losing seven straight road games to the Padres and Dodgers. But they’re 2-1 since returning home, including a 7-5 win over the Phillies in the first game of the series last night.

YouTube video

On Wednesday, the Braves have a chance to feast on a starter they’ve mashed over the years: Taijuan Walker. The 32-year-old pitched six shutout innings in his first start of the season, allowing just three hits and a walk with four Ks. But given that it came against the White Sox, don’t read too much into it.

Career, Walker has allowed current ATL batters to hit .349 with a 1.028 OPS in 83 at-bats. He’s allowed homers to Bryan De La Cruz, Austin Riley, and Michael Harris II twice.

  • Pick: Braves moneyline (-135)

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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