Clemson vs Alabama Odds – Crimson Tide Open as Betting Favorites in Elite Eight

• The #6 Clemson Tigers pulled off their third straight upset to reach the Elite Eight
• The Tigers will face the #4 Alabama Crimson Tide with a berth in the Final Four on the line
• See the opening Clemson vs Alabama odds for Saturday’s game at crypto.com Arena in LA

Picked by many – including oddsmakers – to lose in the first round, the #6 Clemson Tigers have won three straight as moneyline underdogs to reach the school’s first Elite Eight since 1980. The Tigers will face the West Region #4 Alabama Crimson Tide on Saturday at crypto.com Arena for a spot in the Final Four.

To no one’s surprise, the Tigers are underdogs once again in the opening Clemson vs Alabama odds.

Clemson vs Alabama Odds

The Clemson vs Alabama line has opened at Alabama -1.5 with the Tide -125 on the moneyline. The game total is at 165.

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Alabama was +1000 to win the West Region on Selection Sunday, while Clemson was a +4000 longshot in the Final Four odds.

Clemson Outlasts Arizona

Clemson has used a trio of dominant first halves to book its ticket to the Elite Eight.

In the first round, the Tigers led #11 New Mexico 42-28 at the break before cruising to a 77-56 win; in the second round, Clemson opened a 35-25 lead on #3 Baylor and held on for a 72-64 win; in the Sweet 16, the Tigers held a 39-31 lead on #2 Arizona and, despite falling behind by one (46-45) five minutes into the second half, stormed back to earn a 77-72 win.

Chase Hunter had a team-high 18 points against the Wildcats, while center PJ Hall added 17 and a team-leading eight rebounds.

The Tigers showed that they had this type of run in them early in the season. Clemson started the year 11-1 win victories over Boise State (85-68 home), Alabama (85-77 away), Pitt (79-70 away), South Carolina (72-67 home), and TCU (74-66 neutral).

But many left the Tigers for dead after they went just 10-10 the rest of the way, and bowed out to Boston College (71st at KenPom) in the first round of the ACC Tournament.

Clemson did manage to split its two meetings with UNC in the regular season, dropping a low-scoring 65-55 verdict at home on Jan. 6, but repaying the favor in Chapel Hill on Feb. 6 with an 80-76 road win.

Alabama Comes Back to Upset UNC

The Crimson Tide’s Final Four chances were on life support against #1 UNC at halftime, trailing the Tar Heels by eight at the break. But a consummate team effort allowed Alabama to come all the way back for a 89-87 win as 4.5-point underdogs. Grant Nelson led the Tide with 24 points while Aaron Estrada (19), Rylan Griffen (18), and Mark Sears (18) all approached 20 as well.

The offensive explosion was just the latest for Alabama’s electric offense. The Tide trounced #13 Charleston (109-96) in the first round and then survived a 72-61 decision against #12 Grand Canyon in the round of 32.

Led by Mark Sears (21.5 PPG), Alabama rates fourth in offensive efficiency, but a lowly 101st on defense. Clemson beat the Tide 85-77 in Alabama during the regular season.