Red Sox vs Orioles Predictions, Odds & Starting Pitchers (April 26)

By John Perrotto in MLB Baseball
Published:

- The Orioles are -118 home favorites over the Red Sox on Wednesday
- Tanner Houck (3-0, 4.29) will pitch for the Red Sox against the Orioles’ Tyler Wells (0-1, 2.70)
- A look at the Red Sox vs Orioles prediction and odds can be found below
After getting cooled off Tuesday night, the Baltimore Orioles will try to win the deciding game of a three-game series against the Boston Red Sox at 1:05 p.m. ET Wednesday at Oriole Park at Camden Yards.
The Orioles (15-8, 8-4 home) lost to the Red Sox 8-6 on Tuesday night, ending their seven-game winning streak and losing for just the second time in 11 games. The Red Sox (13-12, 6-6 road) won for the fourth time in their last six games.
Red Sox vs Orioles Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
Boston Red Sox | +100 | -1.5 (+160) | Over 8.5 (-105) |
Baltimore Orioles | -118 | +1.5 (+194) | Under 8.5 (-110) |
The Orioles are -118 moneyline favorites over the Red Sox on Wednesday in the MLB odds, giving Baltimore an implied win probability of 54.13%. Boston has +8000 World Series championship odds and the Orioles are listed at +13000.
It could be a wet day in Baltimore as the weather forecast calls for a 70% chance of thunderstorms with a high of 66 and southeast wind at 5-10 mph.
Odds as of April 25th at FanDuel Sportsbook.
Red Sox vs Orioles Probable Pitchers
Tanner Houck (3-0, 4.29) will start for the Red Sox against Tyler Wells (0-1, 2.70). Houck will be pitching on six days of rest and Wells on five.
Houck vs Wells
3-0 | Record | 0-1 |
4.29 | ERA | 2.70 |
3.57 | xERA | 2.95 |
1.24 | WHIP | 0.69 |
2.75 | SO/W | 8.00 |
Houck stayed undefeated when he beat the visiting Minnesota Twins last Thursday. He went seven innings and gave up three runs, six hits and one walk while striking out seven.
Against the Orioles, Houck has a 3-1 record and 1.75 ERA in six career games (two starts).
Houck won his lone road start of the season on April 8 when he held the Detroit Tigers to two runs in five innings. Houck has won all three starts in the day with a 4.24 ERA. The Red Sox have won in each of his four starts in 2023.
Wells pitched seven shutout innings against the Tigers last Friday at Camden Yards but did not figure in the decision. He allowed three hits while striking out five and walking one.
#Orioles Tyler Wells
2023 Pitch Quality ⭐️
Cutter 5.72 QOPA (Top 1% MLB) ✅
Slider 5.19 QOPA (Top 4% MLB) ✅
Curveball 5.47 QOPA (Top 6% MLB) ✅
ChangeUp 5.14 QOPA (Top 10% MLB) ✅@TylerW13 @Jim22Palmer @kevinnbrown @realbenmcdonald #Birdland pic.twitter.com/k9MBO1P7O3— MLB Quality of Pitch (@qopbaseball) April 22, 2023
Wells is 1-0 with a 2.57 ERA in his career against the Red Sox in six games (one start).
In two starts at home this season, Wells is 0-1 with a 2.77. He has made one start in the day and took the loss April 9 to the New York Yankees when he yielded four runs in six innings. The Orioles are 2-1 in Wells’ starts.
Batting Average vs Starting Pitchers
Red Sox Batters | Batting Average vs Tyler Wells |
---|---|
Rob Refsnyder | 1.000 |
Reese McGuire | .500 |
Raimel Tapia | .250 |
Enrique Hernandez | .200 |
Alex Verdugo | .000 |
Rafael Devers | .000 |
Christian Arroyo | .000 |
Orioles Batters | Batting Average vs Tanner Houck |
Jorge Mateo | .500 |
Terrin Vavra | .500 |
Austin Hays | .400 |
Ryan McKenna | .333 |
Anthony Santander | .286 |
Ramon Urias | .250 |
Ryan Mountcastle | .222 |
Cedric Mullins | .200 |
Adam Frazier | .200 |
Adley Rutschman | .000 |
Gunnar Henderson | .000 |
The Red Sox’s Alex Verdugo is 0 for 6 lifetime against Wells. The Orioles’ Austin Hays is 2 for 5 off Houck with two walks.
Red Sox vs Orioles Betting Trends
Jarren Duran hit a grand slam and went 3 for 4 to lead the Red Sox over the Orioles on Tuesday night. Masataka Yoshida added two hits.
Red Sox second baseman Christian Arroyo left the game with right hamstring tightness after missing one game because of the injury. He is questionable for Wednesday.
Catcher Reese McGuire returned to action after sitting out two games with a sore hand. He went 1 for 3 with two RBIs.
Duran Slam. pic.twitter.com/n0NDBcofI4
— Red Sox (@RedSox) April 25, 2023
Infielder Yu Chang was placed on the injured list with a left hamate fractured before the game. Infielder/outfielder Emmanuel Valdez was recalled from Triple-A Pawtucket.
Cedric Mullins hit a slam for the Orioles and Gunnar Henderson and Jorge Mateo also homered. Henderson, Ryan Mountcastle and Terrin Vavra had two hits apiece. Mountcastle’s AL MVP odds are +10000
Hays left the game with a bruised hand. He was injured while trying to bunt and is questionable for Wednesday,
Red Sox vs Orioles Last 10 Games
Date | Home Team | Away Team | Score |
---|---|---|---|
4/25/23 | Orioles | Red Sox | BOS, 8-6 |
4/24/23 | Orioles | Red Sox | BAL, 5-4 |
4/2/23 | Red Sox | Orioles | BOS, 9-5 |
4/1/23 | Red Sox | Orioles | BOS, 9-8 |
3/30/23 | Red Sox | Orioles | BAL, 10-9 |
9/29/22 | Red Sox | Orioles | BOS, 5-3 |
9/28/22 | Red Sox | Orioles | BOS, 3-1 |
9/27/22 | Red Sox | Orioles | BOS, 13-9 |
9/26/22 | Red Sox | Orioles | BAL, 14-8 |
9/11/22 | Orioles | Red Sox | BOS, 1-0 |
The Red Sox have won three of five games from the Orioles this season and are 79-50 against them since 2016.
Red Sox vs Orioles Prediction
Wells has been excellent for the Orioles so far this season and Houck’s peripheral stats suggest he is pitching well even better than his 3-0 record would indicate. Let’s play the under here.
Pick: Under 8.5 (-115)
Season Record: 12-4 (+6.1 units) ML; 1-2 (-1.0 units) RL; 12-6 (+5.1 units) overall

Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.