Andrey Rublev vs Novak Djokovic Picks & Odds – Australian Open Quarterfinals

• It’s Andrey Rublev facing Novak Djokovic in the Australian Open quarterfinals on Wednesday at 3:30 am EST
• Nole is 2-1 against the Russian
• Who takes this match? Read on for the odds, preview, and Andrey Rublev vs Novak Djokovic prediction

The 2023 Australian Open Quarterfinals will be center stage on Wednesday for one of the best matches of the lot. No. 5 Andrey Rublev will clash with tournament favorite, No. 4 Novak Djokovic for their third-ever meeting. The action gets started at 3:30 am EST. Keep reading for the Andrey Rublev vs Novak Djokovic prediction.

Rublev came out on top in a five-set thriller with Dane Holger Rune after a whopping 3 hours and 37 minutes. He bowed out in the round of 32 at Melbourne Park last year. As for Djokovic, he defeated Aussie Alex De Minaur and has dropped just one set through the opening four rounds.

Rublev vs Djokovic Aussie Open Odds

Odds as of January 23rd at FanDuel. Use this FanDuel promo code to bet on all Aussie Open matches.

By no surprise, Nole is a heavy -800 moneyline favorite while Rublev sits at +570 in the Rublev vs Djokovic odds.

Djokovic beat the Russian in both the 2021 and 2022 editions of the ATP Nitto Finals in Italy, while Rublev took down the Serb in Belgrade last year in the final of that tournament.

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Rublev vs Djokovic Match Preview

Rublev will be looking to advance to a Grand Slam major for the very first time here with an upset win over Djokovic. The furthest the 25-year-old has progressed to this point is the quarters of the Aussie Open, US Open, and French Open. In this tournament, he’s looked really good and eliminated several quality opponents along the way. That list includes Dominic Thiem, Emil Ruusuvuori, Dan Evans, and Rune on Sunday.

This match against the Dane was actually the first top-10 encounter of the competition and it certainly didn’t fail to live up to the hype, ending 6-3, 3-6, 6-3, 4-6, 7-6(11-9). Rublev even faced two match points but managed to stay alive. In the fifth set, the Russian trailed 2-5 and clawed his way back, finishing off Rune with a backhand that clipped the net and just dribbled over.

Rublev vs Djokovic Head-to-Head

Djokovic is back in Melbourne and the fans are loving it. He’s coming into this tournament in fine form and has continued to dominate. With Rafael Nadal already out, the 21-time Grand Slam winner is the clear favorite in the Australian Open odds. And to be frank, he’s hardly been tested yet, cruising into the quarters.

While there were some concerns with Nole’s hamstring through the first three rounds, he showed absolutely no discomfort against De Minaur, truly dominating him, 6-1, 6-2, 6-2. The 35-year-old won nearly 50% of De Minaur’s serving points, putting together a flawless performance.

"What we saw was as good as he could possibly move."

The panel discusses the doubts over Novak Djokovic's injury saga – and his parting shot for Alex de Minaur. 👀

🖥️ #AusOpen LIVE | https://t.co/80XjQpwd6J#9WWOS #Tennis pic.twitter.com/Gxzf09X2xF

— Wide World of Sports (@wwos) January 23, 2023

Djokovic’s toughest test comes against Rublev, but he’s got all the confidence in the world at the moment. Nole can just smell the semis and he’s already 9-0 on the season. That includes a title in Adelaide just before the Aussie Open.

Andrey Rublev vs Novak Djokovic Prediction

Although Rublev will fancy his chances here, I don’t see him getting by Djokovic, who simply knows this 22nd title is just waiting for him after Rafa exited early. However, the Russian should be able to take a set. Bet Nole in four.

Rublev vs Djokovic Picks: Djokovic to win 3-1 (+240)