Cincinnati Bengals vs Buffalo Bills Odds, Predictions and Best Bets for Divisional Round Playoffs

By John Perrotto in NFL Football
Updated: January 22, 2023 at 8:28 am ESTPublished:

- The Bills are six-point home favorites over the Bengals on Sunday in an AFC divisional-round playoff game in the Bengals vs Bills picks
- The Bengals are on a nine-game winning streak and the Bills have won eight in a row
- A look at the Bengals vs Bills odds and matchup can be found below with a prediction
Three weeks after the two teams were part of one of the scariest moments in NFL history, the Cincinnati Bengals visit the Buffalo Bills in an AFC divisional round playoff at 3 p.m. ET Sunday at Highmark Stadium in Orchard Park, N.Y.
The regular season meeting between the teams on Jan. 2 in Cincinnati was stopped and ruled a no-contest after Bills safety Damar Hamlin collapsed and went into cardiac arrest in the first quarter.
The Bengals (13-4, 6-3 road) enter this game on a franchise-record nine-game winning streak that includes beating the Baltimore Ravens 24-17 in a wild-card playoff game last Sunday at home. The Bills (14-3, 8-1 home) are on an eight-game streak, their longest since 2020, after getting past the Miami Dolphins 34-31 last Sunday.
CBS will broadcast the game.
Bengals vs Bills Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Cincinnati Bengals | +200 | +6 (-110) | Over 49 (-110) |
Buffalo Bills | -250 | -6 (-110) | Under 49 (-110) |
Odds as of January 21st at BetMGM. Claim the BetMGM promo code for the NFL Playoffs.Â
The Bills are favored by six points and are -250 picks on the moneyline in the Bengals vs Bills odds, giving them an implied win probability of 71.43%. In the Super Bowl championship odds, Buffalo is listed at +350 and the Bengals at +800.
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Bengals vs Bills Recent History
The last official game between the teams resulted in the Bills winning 21-17 on Sept. 22, 2019 at home. Buffalo quarterback Josh Allen threw for 243 yards and a touchdown.
The Bengals have won four of the past six matchups.
Bengals Offense vs Bills Defense
The Bills’ secondary is banged up and faces a tough matchup. The Bengals were fifth in the NFL in passing offense during the regular season and quarterback Joe Burrow has an array of top-flight wide receivers at his disposal.
Ja’Marr Chase had 1,046 receiving yards in the regular season despite missing four games with a hip injury. He opened the playoffs with nine catches for 84 yards and a touchdown last week.
Ja’Marr Chase makes it look so easy pic.twitter.com/ARKbv9ORL6
— Elite Picks (@ElitePicks_DFS) January 8, 2023
Burrow has +600 NFL MVP odds.
The Bills are hurting in the secondary. Cornerback Dane Jackson (knee) was injured in last week’s game and safety Jordan Poyer is playing through a series of injuries.
The Bengals have injury problems, too, as they are missing three starting offensive linemen. Right tackle La’el Collins (knee) went out on Dec. 24, right guard Alex Cappa (ankle) was lost on Jan. 8 and left tackle Jonah Williams (knee) went down last week.
Bills Offense vs Bengals Defense
Which version of Allen shows up Sunday will likely determine the Bills’ fate. He is as dynamic as any quarterback in the NFL but also prone to mistakes.
Allen was at his best and worst last week. He threw three touchdown passes but was also intercepted twice and lost a fumble that was returned for a score.
Allen has 38 TD passes this year while throwing for 4,635 yards. However, he also has 22 turnovers with 16 picks and six fumbles.
Still can’t figure this one out!
Someone with a defensive brain explain why you go cover 0 on 3rd and 15 with Bills way out of FG range, knowing Josh Allen throws 🎯
— Greg Camarillo (@catchcamarillo) January 20, 2023
The Bengals beat the Ravens on a turnover when Sam Hubbard returned a Tyler Huntley fumble 98 yards for the tiebreaking touchdown last week in the fourth quarter. It was the longest fumble return for a score in NFL postseason history.
Cincinnati vs Buffalo Injury Report
Cappa and Williams are listed as out for the Bengals and cornerback Tre Flowers (hamstring) is doubtful. Max Scharping will start for Capps and Williams will be replaced by Jackson Carman, normally a guard.
Jackson is expected to play for the Bills and wide receiver Isaiah McKenzie (hamstring) should also be back after sitting out last week. Defensive tackles Jordan Phillips (shoulder) and DaQuan Jones (calf) are questionable.
Bengals vs Bills Prediction
The Bills are 13-1 all-time at home in the playoffs and that record is hard to ignore. However, the Bengals have played just as well as Buffalo over the last two months and have the quarterback in Burrow to at least keep things close on the road in our Bengals vs Bills picks.
Pick: Bengals +6 (-110)
Season record: 6-7 (-1.7 units) ATS), 1-0 (+1.3 units) ML

Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.