NFL Week 17 Odds – Opening Betting Lines & Spreads for All Games

• NFL Week 17 begins with the Cowboys visiting the Titans on Thursday Night Football
• The Chiefs are the biggest opening favorites at 13.5 points over the Broncos
• A look at all the opening NFL Week 17 odds can be found below with predictions

NFL Week 17 begins with Thursday Night Football as the Dallas Cowboys visit the Tennessee Titans at Nissan Stadium in Nashville.

The Cowboys (11-4) have opened as 10-point favorites after knocking the Philadelphia Eagles, the team with the best record in the NFL, 40-34 on Saturday. The Titans (7-8) are on a five-game losing streak after falling to the Houston Texans 19-14 on Saturday.

Sunday Night Football features an AFC North matchup with the Baltimore Ravens (10-5) favored by 3.5 points at home over the Pittsburgh Steelers (7-8). The Buffalo Bills (12-3) visit the Cincinnati Bengals (11-4) on Monday Night Football as one-point favorites.

The NFL odds will be updated throughout the week.

NFL Week 17 Opening Odds

Odds as of December 25th at FanDuel. Claim a FanDuel Sportsbook promo code. 

The Chiefs are Week 17’s biggest favorites at 13.5 points over the Broncos. The slimmest favorites are the Bills by one point over the Bengals.

The highest over/under is 51.5 points for Bears vs Lions. The lowest total of 36 for Steelers vs Ravens.

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Bills vs Bengals Early Odds & Prediction

Both playoff-bound teams are rolling coming into this Monday night matchup. The Bengals (11-4) have won seven games in a row and the Bills (12-3) are on a six-game winning streak.

The Bills beat the Bears 35-13 in Chicago on Saturday to wrap up the AFC East title.

Devin Singletary and James Cook highlighted the victory with long touchdown runs in the third quarter. Josh Allen passed for one TD and ran for another.

Let Jimbo Cook!

📺: @NFLonCBS pic.twitter.com/P7Ge5CgByB

— Buffalo Bills (@BuffaloBills) December 24, 2022

The Bengals built a 22-0 lead then held off the New England Patriots 22-18 on Saturday on the road. Cincinnati maintained a one-game lead over the Baltimore Ravens in the AFC North.

Joe Burrow threw three touchdown passes to lead the Bengals. He finished 40 of 52 for 375 yards and was intercepted twice.

This should be quite a game but look for the Bills to pull it out in the end.

Pick: Bills -1 (-105)

Dolphins vs Patriots Early Odds & Prediction

Both teams will try to stop their freefalls and keep their playoff hopes alive when they meet Sunday at Gillette Stadium in Foxborough, Mass. The Dolphins (8-7) are on a four-game losing streak and the Patriots (7-8) have lost four of their last five.

The Patriots nearly came all the way back from their 22-point deficit to beat the Bills. Down 22-18, New England had the ball at the Cincinnati 5-yard line with just over a minute when Rhamondre Stevenson was hit by Vonn Bell and fumbled with the Bengals’ Josh Tupou recovering.

Joy!#BudLightCelly | @budlight pic.twitter.com/tB7En84zdZ

— Cincinnati Bengals (@Bengals) December 24, 2022

The Dolphins dropped a 26-20 decision to the Green Bay Packers on Sunday at home. Tua Tagovailoa threw three interceptions, all in the fourth quarter.

Even though the Patriots are playing poorly, this line still seems a little high considering the Dolphins’ late-season collapse. Let’s try the home dogs here.

Pick: Patriots +2.5 (-115)

49ers vs. Raiders Early Odds & Prediction

The 49ers (11-4) have now extended their winning streak to eight games as they visit the Las Vegas Raiders on Sunday at Allegiant Stadium. The Raiders (6-9) have lost two of their last three games.

Brock Purdy threw two long touchdown passes to tight end George Kittle on Saturday as the 49ers beat the visiting Washington Commanders 37-20. Purdy has two TD passes in four straight games since replacing the injured Jimmy Garoppolo.

Kittle’s scored covering 34 and 33 yards.

The Raiders had a late-game loss to the Steelers 13-10 in Pittsburgh on Saturday night. Kenny Pickett threw a 14-yard touchdown pass to George Pickens with 46 seconds remaining.

Still harboring faint playoff hopes, the Raiders have more at stake in this game. Figure on them at least staying close.

Pick: Raiders +5.5 (-108)