Week 10 NFL Picks Against the Spread – Early Lines to Target

By Robert Duff in NFL Football
Published:

- For just the third time since the start of the 2018 NFL Season, the Green Bay Packers are home underdogs
- The Tennessee Titans are 6-0 ATS in their past six games
- Which NFL teams should be considered the best bets in the early Week 10 NFL picks against the spread? Check out the following story to discover this answer
Who would’ve thought that in the NFL Week 10 against the spread picks we’d be debating whether Aaron Rodgers and the Green Bay Packers are a good play as 5.5 home underdogs at Lambeau Field?
The NFL odds aren’t working on the side of the Packers this season. Green Bay has lost five in a row straight up to fall to 3-6 on the season. And because of that, for just the third time in five years, the Pack will be getting points at home. The Dallas Cowboys are 5.5-road favorites at Green Bay in Week 10.
The hottest ATS team in the NFL right now is the Tennessee Titans. Even though their five-game win streak came to a halt at Kansas City in Week 9, the Titans were extending their ATS unbeaten run to 6-0.
Both the Cowboys and Titans are teams worth considering as best bets in the NFL Week 10 ATS picks.
Week 10 NFL Picks Against the Spread
Matchup | Spread | Pick | Units Risked |
---|---|---|---|
Cleveland Browns vs Miami Dolphins | MIA -4 | CLE | 1 |
Denver Broncos vs Tennessee Titans | TEN -3 | TEN | 1 |
Dallas Cowboys vs Green Bay Packers | DAL -5.5 | DAL | 1 |
Odds as of November 8 at Caesars Sportsbook. Get this Caesars Sportsbook bonus code to bet on the NFL.
Our top NFL ATS picks this week in the table above will feature plays on the Browns, Titans and Cowboys.
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NFL ATS Pick 1: Browns (+4) vs Dolphins
The 6-3 Dolphins are 6-0 straight up and 4-2 against the spread in games started and finished this season by quarterback Tua Tagovailoa.
The Browns have given themselves a real opportunity.
Think of it as a 3-game season:
Dolphins
Bills
BuccaneersIf they can get 2 out of 3 and move to 5-6, they have 6 pretty winnable games in a row with Deshaun Watson. #Browns
— Hayden Grove (@H_Grove) November 1, 2022
However, in the past two weeks, while Miami has won, the Dolphins were hard-pressed to stave off two really bad teams in the Detroit Lions and Chicago Bears. They failed to cover against Chicago. After Cleveland’s MNF dismantling of the Bengals, there’s every evidence that the Browns could prove a handful for Miami.
Pick: Cleveland Browns +4 (-110), 1 unit
NFL ATS Pick 2: Titans (-3) vs Broncos
Denver is coming off the bye week. Tennessee is returning home from a hard-fought overtime loss at Kansas City.
Considering those two scenarios, maybe you could make a case for the Broncos pulling the upset here. Well, maybe you could make that case if hadn’t seen any Broncos games this season.
Pick: Tennessee Titans -3 (-110), 1 unit
NFL ATS Pick 3: Cowboys (-5.5) vs Packers
Dallas is 6-1 over the past seven games. The lone loss suffered by the Cowboys was at unbeaten Philadelphia.
The Green Bay Packers fired Mike McCarthy the week after they fell to 4-7-1 in 2018.
If Mike McCarthy’s Dallas Cowboys beat the Packers next Sunday afternoon then Green Bay will fall to 3-7.
— RJ Ochoa (@rjochoa) November 6, 2022
Green Bay is 8-1 SU and 7-2 ATS in the last nine games against Dallas. However, the last three times that the Cowboys have covered against the Packers, all three games were played at Lambeau Field. It’s the first time Dallas is favored at Green Bay since 2009.
Pick: Dallas Cowboys -5.5 (-110), 1 unit
- ATS season record 17-9-1
NFL Week 10 Against the Spread Quick Picks
- Falcons (-3) vs Panthers:Â Atlanta won two weeks ago over Carolina but didn’t cover as 4-point favorites.
- Seahawks (+2.5) vs Buccaneers:Â The Seahawks keep winning and the oddsmakers keep picking against them.
- Chiefs (-9.5) vs Jaguars:Â Kansas City will find covering at home against Jacksonville is much easier than covering at home against Tennessee.
- Bills (-6.5) vs Vikings:Â Favorites in the Super Bowl odds, Buffalo is 0-2 ATS the past two weeks. Despite leading the NFC North, Minnesota is 3-4-1 ATS.
- Giants (-6.5) vs Texans:Â Giants are 3-1 both SU and ATS at home this season.
- Lion (+3) vs Bears:Â Detroit is 4-1-1 ATS in the last six visits to Soldier Field.
- Raiders (-6) vs Colts: Indianapolis fired coach Frank Reich, replacing him with former Colts center Jeff Saturday, who’s only coached high school football. And you thought the Raiders were an organization in disarray.
- Rams (-3) vs Cardinals:Â The Rams are home, so we’ll go with them.
- 49ers (-7) vs Chargers:Â San Francisco is looking like a different team with Christian McCaffrey in the backfield.
- Eagles (-11) vs Commanders:Â Remember a couple of years ago when Washington went to Pennsylvania, stunned the unbeaten Steelers and Pittsburgh’s season went completely off the rails? Yeah, that isn’t going to happen to the Eagles.

Sports Writer
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.