New Orleans Saints vs Arizona Cardinals Odds, Lines, Picks and Predictions for Week 7 Thursday Night Football

• In the New Orleans Saints vs Arizona Cardinals odds for the Week 7 TNF game, Arizona is a 2-point home favorite
• It’s the first time all season that the Cardinals are favored at home
• Likewise, it’s the first time all season that the Saints are playing as road underdogs

As the Arizona Cardinals (2-4, 3-3 ATS) and the New Orleans Saints (2-4, 2-4 ATS) prepare for the NFL Week 7 TNF game, perhaps the best news of all is that traditionally, both of these teams score a lot of points when they face each other.

In the past five meetings at State Farm Stadium, four Saints vs Cardinals games have gone over. Over the last eight meetings between these two NFL rivals, at least one team has topped 30 points.

Considering the last two TNF games – a 12-7 Washington win at Chicago and a 12-9 Indianapolis verdict at Denver, over bettors will be delighted by this news. New Orleans is 5-1 on the total this season. However Arizona is just 1-4-1.

Oddsmakers are setting the Cardinals as 2-point home favorites. Arizona is 0-3 against the spread at home this season.

Saints vs Cardinals Odds

Odds as of October 19 at Caesars Sportsbook. See the available Caesars Sportsbook promo code for the NFL here

The Cardinals, set as -110 moneyline favorites, are 0-3 straight up at home this season. New Orleans, a +130 underdog, is 1-1 SU on the road.

Kickoff at State Farm Stadium is set for 8:15 pm ET on Thursday, October 20. The weather forecast is calling for clear skies, 4 mph wind and a temperature of 86 degrees.

The game is airing exclusively on Amazon Prime as part of a new partnership for Thursday Night Football with Amazon.

New Orleans vs Arizona NFL Betting Trends

In NFL public betting trends, people are going with the Cardinals on the point spread. Arizona is drawing 60% of handle and 56% of bets. There’s a difference of opinion in moneyline wagering, though. The public is placing 51% of the handle on Arizona and 52% of bets on New Orleans. The public is leaning toward the over in total wagering. The over is getting 79% of handle and 55% of bets.

Chris Olave & DeAndre Hopkins are back just in time for TNF.#NOvsAZ — Thursday 8:15pm ET on Prime Video
Also available on NFL+ https://t.co/fK7vaWAizI pic.twitter.com/wj1lW4WUTE

— NFL (@NFL) October 19, 2022

The NFL team trends entering Week 7 are showing that the point spread on this game has shortened from an opening line of Arizona -2.5. The total has lengthened one point from an opening line of 44.5 points.

New Orleans is showing a betting line of +8000 in the Super Bowl odds. Bettors can access +12500 odds on Arizona in this betting market. The Saints are the +1300 third-betting choice to win the NFC South. In the NFL division odds, the Cardinals are +1200 third choice in the NFC West.

Slow Starts Hurting Cardinals

Arizona has continued to dig holes. The Cardinals have been outscored 89-29 in the first half this season. QB Kyler Murray is struggling, with six TD passes against four interceptions. In two games this season, the Cardinals have failed to score an offensive TD.

“He’s an electric player.”

Arizona Cardinals QB Kyler Murray is excited to have WR1 DeAndre Hopkins back pic.twitter.com/xV0MiiGyjx

— PHNX Cardinals (@PHNX_Cardinals) October 18, 2022

Things aren’t faring much better when the Saints have the football. New Orleans has turned the ball over an NFL-high 13 times. QB Andy Dalton has helped in this regard. In three starts, he’s only been picked off once. QB1 Jameis Winston has thrown five interceptions.

Both Teams Riddled With Skill Position Injuries

Everywhere you look on the New Orleans roster, there are ailments. Both starting QB Jameis Winston (back/ankle) and backup Andy Dalton (back) are listing as questionable. Dalton will get the start.

Wide receiver Chris Olave is cleared from concussion protocol and should play. WR Michael Thomas (foot), Jarvis Landry (ankle) and Keith Kirkwood (ankle) are questionable, as are RB Mark Ingram II (knee) and TE Adam Trautman (ankle). LG Andrus Peat (chest) is out. Four backup OL are either questionable or on IR. On defense, both starting CB, All-Pro Marshon Lattimore (abdomen) and Paulson Adebo (knee) are questionable.

Marquise Brown pre-injury pace: 122-1374-9. Dude was balling. pic.twitter.com/tEeA7NJ4AL

— Ian Hartitz (@Ihartitz) October 17, 2022

The Cardinals are getting WR DeAndre Hopkins back from NFL suspension. However, WR Marquise Brown (foot) is out. Three RBs – James Conner (ribs), Eno Benjamin (foot) and Darrel Williams (knee) – are questionable, as are LG Justin Pugh (elbow) and C Rodney Hudson (knee).

Kicker Mat Prater (hip) is questionable, as are LB Dennis Gardeck (ankle) and Zaven Collins (shoulder) and SS Jalen Thompson (hamstring).

Saints vs Cardinals Prediction

It’s difficult to get past the home woes of the Cardinals. If they don’t win this game, a calendar will have passed since Arizona’s last home victory. The Cardinals beat the Houston Texans 31-5 at State Farm Stadium on October 24, 2021.

The Cardinals and Saints got a few similarities at the moment.

Disappointing 2-4 start to the season.
Dealing with a ton of injuries.
Jury still out on the head coach.
One of the oldest rosters in the league.

— Chris Rosvoglou (@RosvoglouReport) October 19, 2022

Since then they are 0-8 SU and 1-7 ATS on their home field. That includes 0-3 SU and 1-2 ATS this season. However, Arizona is 3-1 SU and ATS in the past four home games against the Saints. All four of those games have also gone over.

• Pick: New Orleans Saints -2 (-110), 1 unit
• TNF record (0-0 ML, 1-4 ATS, 1-0 O/U)