Brewers vs Pirates Odds and Picks (April 28)

By John Perrotto in MLB Baseball
Updated: April 28, 2022 at 9:04 pm EDTPublished:

- The Brewers are -163 road favorites over the Pirates on Thursday
- Freddy Peralta (0-1, 7.50) will pitch for the Brewers against left-hander Jose Quintana (0-1, 3.86)
- A look at the Brewers vs Pirates odds and matchups can be found below with a prediction
The Milwaukee Brewers will go for a three-game series sweep as they visit the Pittsburgh Pirates at 12:35 p.m. ET Thursday at PNC Park.
The Brewers (12-7, 8-4 road) rallied for a 3-1 win on Wednesday night, their eighth victory in the last 10 games as they lead the National League Central. The Pirates (8-10, 4-5 home) have lost three of four.
Brewers vs Pirates Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
Milwaukee Brewers | -163 | -1.5 (+105) | Over 7.5 (+100) |
Pittsburgh Pirates | +153 | +1.5 (-125) | Under 7.5 (-120) |
Odds as of April 27th at Caesars Sportsbook.

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The Brewers are -163 favorites on the moneyline, giving them a 61.98% expected win probability. It should be a nice day in Pittsburgh with sunny skies, a high temperature expected to be 56 degrees and northwest wind at 5-9 mph.
The Brewers’ World Series odds are +1400 while the Buccos are quite the longshot at +40000
Milwaukee vs Pittsburgh Probable Pitchers
Freddy Peralta (0-1, 7.50), who has +8000 NL Cy Young odds, will start for the Brewers against left-hander Jose Quintana (0-1, 3.86). Both will be pitching on five days of rest.
Peralta vs Quintana
0-1 | Record | 0-1 |
7.50 | ERA | 3.86 |
4.96 | xERA | 5.70 |
1.75 | WHIP | 1.50 |
2.00 | SO/W | 1.00 |
Peralta is coming off a no-decision last Friday against the Phillies in Philadelphia. He allowed one run and three hits in five innings with six strikeouts and two walks.
Against the Pirates, Peralta is 2-1 lifetime with a 3.19 ERA in 14 games (five starts). He has 2-1 record at PNC Park and a 2.70 ERA in eight games (three starts).
What a night for Freddy Peralta. 👏 pic.twitter.com/2WtQkuHFBk
— MLB (@MLB) June 5, 2021
Peralta will be making his third road start after having no decisions and a 4.00 ERA in his first two. He is 0-1 with a 3.86 ERA in two starts during on the road and the day.
Bryan Reynolds, who was activated from the COVID-19 IL on Wednesday, is 6 for 13 (.462) against Peralta with a double and triple. Ben Gamel is 3 for 6.
Two key pieces of the rotation? Miguel Yajure and Jose Quintana get some work in at LECOM Park. pic.twitter.com/UWH3uujEcB
— Jason Mackey (@JMackeyPG) March 15, 2022
Quintana also had a no-decision last Friday when he gave up two runs on three hits in 4.2 innings to the Cubs in Chicago. He struck out three and walked.
Quintana has had success against the Brewers with a 9-4 record and 2.78 ERA in 18 games (17 starts). He is 0-1 with a 3.86 ERA in two starts both at home and in the daylight in 2022.
Hunter Renfroe has two home runs off Quintana while going 3 for 10 (.300) but Kolten Wong is 1 for 12 (.083).
Brewers vs Pirates Betting Outlook
Neither team had a hit until the sixth inning Wednesday night and finished with a total of five.
Tyrone Taylor hit a tiebreaking RBI single in the seventh inning as the Brewers overcame a 1-0 deficit. The Brewers managed just four hits on a 40-degree night with Wong getting the first with a one-out double in the sixth inning.
.@tyrone_taylor15 for the lead! pic.twitter.com/9W9YqGBMlU
— Milwaukee Brewers (@Brewers) April 28, 2022
Reynolds had the Pirates’ lone hit, a sixth-inning infield single. It was a hard shot that deflected off the glove of diving third baseman Mike Brosseau.
Josh Hader notched his MLB-leading 10th save in as many opportunities.
The Brewers are 5-0 against the Pirates this season and hold a commanding 39-14 advantage in the series since the start of the 2019 season.
Brewers vs Pirates Last 10 Games
Date | Home Team | Away Team | Score |
---|---|---|---|
4/27/22 | Pirates | Brewers | MIL, 3-1 |
4/26/22 | Pirates | Brewers | MIL, 12-8 |
4/20/22 | Brewers | Pirates | MIL, 4-2 |
4/19/22 | Brewers | Pirates | MIL, 5-2 |
4/18/22 | Brewers | Pirates | MIL, 6-1 |
8/15/21 | Pirates | Brewers | MIL, 2-1 |
8/14/21 (2) | Pirates | Brewers | MIL, 6-0 |
8/14/21 (1) | Pirates | Brewers | PIT, 14-4 |
8/4/21 | Brewers | Pirates | MIL, 4-2 |
8/3/21 | Brewers | Pirates | PIT, 8-5 |
Brewers vs Pirates Prediction
The Brewers have certainly had the Pirates’ number in recent years.
However, Peralta is allowing opponent to hit .271 off him after holding them to a microscopic .165 batting average last season. Though most of it came before he began being beset by injuries, Quintana has a good track record against the Brewers and looks like a worthy underdog play here.
Play: Pirates ML +153
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Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.