Real Madrid vs Chelsea Odds & Prediction – Champions League Quarterfinals Leg 2

By Josh Ricker in Soccer News
Published:

- Real Madrid hosts Chelsea in the second leg of their Champions League quarterfinal duel on Tuesday, April 12th at 3:00 pm ET. Real Madrid are +138 moneyline favorites in this match
- Read Madrid currently holds a 3-1 aggregate lead thanks to a magical Karim Benzema hat-trick in the first leg
- Get the Real Madrid vs Chelsea odds, analysis, and betting prediction below
In the second leg of their grandiose Champions League quarterfinal, Real Madrid looks to defend their 3-1 lead at the Bernabéu against Chelsea. Read on for our Real Madrid vs Chelsea prediction.
The reverse fixture obviously went in their favor, but the scoreline might have flattered Los Blancos. In fact, Real Madrid were outshot by Chelsea 20-8, and could only muster up 42% possession. However, in the Champions League sometimes it comes down to just being clinical in front of goal. Carlo Ancelloti’s side did just that.
Now, Chelsea are faced with the even more difficult task of making up a two-goal difference away from home. Thomas Tuchel will have to open up his side and play an exotic brand of attacking football. While they are more than capable of this, their +4,000 Champions League odds convey the hard road ahead.
Real Madrid vs Chelsea Odds
Matchup | Moneyline Odds |
---|---|
Real Madrid | +138 |
Chelsea | +200 |
Draw | +250 |
Odds as of Apr 10th at Barstool Sportsbook
If you’re new to betting on this sport, then take a look at our How to Bet on Soccer page.
In summary, the moneyline odds for this match are in Real Madrid’s favor, but only slightly at +138.

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Over/Under and Spread
Also, there is some value in the over 2.5 goals bet with odds of -117. These sides have hit that over in eight of their last ten matches across all competitions.
Chelsea at -162 is favored on the +0.5 spread for this match.
Real Madrid vs Chelsea Prediction for Quarterfinal Leg 2
Furthermore, the over on total goals should always be the favored result with Karim Benzema on the pitch. The French striker has aged so gracefully and his 37 goals this season do all the talking for him.

Benzema to Score Odds
If you needed any more evidence of his greatness, his 3.78 shot-creating actions per 90 minutes exhibit his ability to create in a variety of scenarios.
Real Madrid vs Chelsea UCL Statistics
2.22 | Goals per game | 2.00 |
1.73 | Expected goals per game | 1.77 |
0.67 | Goals allowed per game | 0.89 |
1.16 | Expected goals allowed per game | 0.93 |
54.2% | Possession % | 62.0% |
89.2% | Passing Accuracy % | 88.1% |
15.9 | Shots per game | 15.6 |
In the first leg, his movement and determination terrorized the Chelsea backline. While his third goal was just a capitalization on a howling mistake from Edouard Mendy, the first two could not have been more world-class.
🎖 Surprise, surprise! @Benzema is the #UCL Player of the week! pic.twitter.com/r7k4s51uKE
— Real Madrid C.F. 🇬🇧🇺🇸 (@realmadriden) April 8, 2022
In fact, on both occasions, he managed to split the likes of Thiago Silva and Antonio Rudiger to head the ball into the Stamford Bridge nets.
Considering he is coming off back-to-back Champions League hat-tricks, it begs the question. Can any team, let alone Chelsea, stop Benzema on his current form? If you’re looking to bet on Benzema’s scoring streak to continue, he is +110 odds as an anytime scorer and +375 to be the first or last scorer in the match.
Chelsea Looking to Ride 6-0 High
Conversely, Chelsea head into this game knowing they have to score at least twice to get this game to extra time. That is no easy task considering ex-Chelsea player Thibault Courtois is in net for Real Madrid. Additionally, Real Madrid have only allowed 26 goals in La Liga and a mind-boggling six in Europe this season.
However, Chelsea should be more confident this week after a goal fest against Southampton at the weekend. The Blues scored six against Fraser Forster, with Timo Werner hitting the post three times.
Two goals and an assist for Mason Mount.
Chelsea are winning 6-0 🤫 pic.twitter.com/aDQ5PG5Nco
— B/R Football (@brfootball) April 9, 2022
This shows that this Chelsea side can open up and play very offensively when asked. Southampton are usually due a 9-0 game at least once in every EPL season, so make of it what you will.
But, what we do know is that this Chelsea side will not go out easily. Kai Havertz and Mason Mount are elite creators and they will put pressure on Real Madrid.
Real Madrid vs Chelsea Projected Lineups and Injuries
Real Madrid Projected Lineup: Courtois, Mendy, Alaba, Nacho, Carvajal, Casemiro, Kroos, Modric, Vinicius, Benzema & Rodrygo
Real Madrid Injuries & Suspensions: Militao, Hazard & Jovic
Chelsea Projected Lineup: Mendy, Alonso, Rudiger, Silva, James, Kante, Kovacic, Mount, Havertz, Ziyech, & Werner
Chelsea Injuries & Suspensions: Chilwell, Azpilicueta, Hudson-Odoi (questionable), Lukaku (questionable)
Real Madrid vs Chelsea Best Bet
Overall, the best bet for this match is the over on 2.5 total goals at -117. Real Madrid are 14-4-2 at home this season, and I do see them advancing. Still, there is huge risk of a draw, but goals should be expected either way.
Pick: Over 2.5 total goals (-117)
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Sports Writer
Josh Ricker is a freelance sports journalist, currently attending the University of Southern Maine (Bachelor of Science in Sports Management and Marketing). He has recently interned with the AA Portland Sea Dogs, and his work has been featured on Fansided, as well as now here on SBD.