Chelsea vs Real Madrid Odds & Prediction – Champions League Quarterfinals Leg 1

• Holders Chelsea host 13-times winner Madrid at Stamford Bridge at 3:00 pm ET on Wednesday
• Londoners reeling after 4-1 hammering  by Brentford while Spanish giant closes in on La Liga title
• See all the odds, previews and best bets for Chelsea vs Real Madrid in the Champions League Quarterfinals Leg 1 below

Chelsea will have to recover from one of the English Premier League’s shock results of the season when it hosts Real Madrid in the Champions League on Wednesday.

Ahead of the last eight clash with the Spanish giants, Tomas Tuchel’s Chelsea side was thrashed 4-1 at home by Brentford last Saturday.

Brentford is in its first season in the English top-flight in 75 years.

Chelsea vs Real Madrid Odds

Odds as of April 5 at Barstool

Madrid had a much more comfortable approach to this massive European occasion – defeating Celta Vigo 2-1 away from home in La Liga last weekend.

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With former Madrid’s Chelsea boss Carlo Ancelotti missing the game with COVID-19, Chelsea is the favorite on the moneyline for a home first-leg win by Barstool Sportsbook at +102.

Meanwhile, Madrid is rated at +290. The draw, furthermore, is a very attractive proposition at +240.

However, neither of these sides is among the leading contenders in the Champions League odds to win the trophy.

The kick-off in London is at 3:00 pm ET.

Chelsea Knocked Out Madrid Last Season

Holders Chelsea overcame Madrid on the way to lifting the trophy last season.

The teams met at the semifinal stage. Chelsea secured a 1-1 first-leg draw in Spain before winning 2-0 at home in the return.

So obviously, the Spaniards will be seeking revenge – as well as hoping to ensure that they capitalize on their stunning last 16 elimination of Paris Saint-Germain.

Suited and booted! Real Madrid's players touch down in London ahead of crunch Champions League quarter-final first leg against Chelsea https://t.co/omaiKPCSC2

— Mail Sport (@MailSport) April 5, 2022

The French team won 1-0 in Paris. But Karim Benzema scored an impressive second-half hat-trick as Madrid roared back to win the return meeting by 3-1.

There is turmoil surrounding Chelsea off the pitch amid the enforced sale of the club by Roman Abramovich – ordered by the UK Government as part of sanctions following the Russian invasion of Ukraine.

However, things had remained calm and progressive on the pitch until the shock hammering by Brentford.

Chelsea coach Tuchel was at a loss to explain the defeat by Brentford.

It brought to an end a run of five straight league wins which had underlined Chelsea’s defensive strength. It conceded just twice during that run while scoring 11 times.

So that left coach Tuchel at a loss to explain the defeat by Brentford – with the German admitting he was baffled by the result.

Now it sits in third place in the EPL. However, its title hopes are over as leader Manchester City has a 14-point gap over the Londoners and are one of the favorites with Liverpool in the EPL odds.

Moreover, Chelsea had been in impressive form in the UCL, too. It eased to a double victory against Lille – winning 2-0 at home and then 2-1 away.

🔵⚪️🔥 Chelsea vs Real Madrid in the UEFA Champions League quarterfinals, tomorrow! Can #CFC get the better of #RMFC in the #UCL again? How to watch live, team news, odds & more ⤵️ #CHERMA https://t.co/ubNw9EOyU5

— NBC Sports Soccer (@NBCSportsSoccer) April 5, 2022

The team also faces an FA Cup semifinal against London rivals Crystal Palace later this month – having lost on penalties in the EFL Carabao Cup final against Liverpool.

Defensively, the side is impressive in the UCL, too – having won its last six home games in the competition and kept a clean sheet every time.

Chelsea vs Real Madrid Statistics

*Stats from UCL 2021-22

Even so, it will have to be very wary of the potent striker Benzema – especially if Madrid land a penalty.

He scored both goals from the spot in the weekend win against Celta Vigo – although he also missed one in the same game.

Benzema Has Hit Five Penalties In Six La Liga Games

Indeed, in the last six La Liga fixtures, he has scored six times – five times from penalties.

Meanwhile, Madrid is closing in on a title win in Spain.

It leads second-placed Barcelona by eight points with eight games remaining.

Yet Barcelona proved its renewed form by beating Madrid 4-0 in the El Clasico derby at the Santiago Bernabeu stadium on March 20.

🗣 “We need everybody on the front foot. It’s a big match, it’s quarter-finals. It’s a big opponent.”

Thomas Tuchel says him and his side need the Chelsea fans to help them against Real Madrid with the Stamford Bridge atmosphere tomorrow. #UCL pic.twitter.com/WoBvIMHSqC

— Football Daily (@footballdaily) April 5, 2022

However, that was Madrid’s only defeat in the last 10 games – with seven wins and two draws.

The manner of the win against Vigo, though, confirmed that Madrid had not fully recovered from the pain inflicted in its HQ by Barcelona.

These teams are old rivals – having met in the European Cup Winners Cup final in 1970-71.

Meanwhile, Benzema is priced at a compelling +225 to get on the scoresheet in London.

The Chelsea forward most favored for a goal is Romelu Lukaku at +230.

When Chelsea met Real Madrid in the Champions League last season..

📽 @ChelseaFC pic.twitter.com/rgjxVysrJ1

— Football Tekkers (@BallTekkers) April 5, 2022

These teams are old rivals – having met way back in the European Cup Winners Cup final in 1970-71.

Chelsea won the trophy with a 2-1 victory in Athens in a replay following a 1-1 draw.

And, to sum, up a draw looks likely again in the UK capital. With so much at stake, this first leg looks like being a tight and cagey affair despite the glamourous nature of the tie.

Pick: Draw +240